Results 101 to 110 of about 4,931,670 (329)
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
FURTHER OBSERVATIONS CONCERNING GROWTH REQUIREMENTS OF HEMOPHILIC BACILLI [PDF]
Francis C. O. Valentine +1 more
openalex +1 more source
The SAR Payload Design and Performance for the GF-3 Mission
This paper describes the C-band multi-polarization Synthetic Aperture Radar (SAR) sensor for the Gaofen-3 (GF-3) mission. Based on the requirement analysis, the design of working modes and SAR payload are given.
Jili Sun, Weidong Yu, Yunkai Deng
doaj +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
The objective of this research was to study the effect of Concurrent Engineering environmental factors and product development performance that measured by overall variablesof financial performance.
Muh Natsir
doaj
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
REQUIREMENT OR RECOMMENDATION? [PDF]
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openaire +2 more sources

