Results 91 to 100 of about 3,794,962 (338)
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Prioritizing Software Requirements by Combining the Usage Monitoring and User Feedback Data
IEEE AccessThe elicitation of requirements for systems in use is known as continuous requirements elicitation. Monitoring and feedback data have been used in the literature for the continuous elicitation and prioritization of requirements. Frameworks and techniques
Syeda S. Tanveer, Zeeshan A. Rana
doaj +1 more source
U-Care: Requirements Elicitation For Ambient Assisted Living [PDF]
, 2009 Western countries are facing similar trends in healthcare: population is aging, life expectations are growing, the number of healthcare professionals is decreasing, cost pressure on healthcare systems is increasing and urbanization is taking place.
Beijnum, B.J.F. van +2 more
core +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Identifying and Modelling Complex Workflow Requirements in Web Applications [PDF]
, 2012 Workflow plays a major role in nowadays business and therefore its requirement elicitation must be accurate and clear for achieving the solution closest to business’s needs. Due to Web applications popularity, the Web is becoming the standard platform
Escalona Cuaresma, María José +5 more
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Arguing satisfaction of security requirements [PDF]
, 2006 This chapter presents a process for security requirements elicitation and analysis, based around the construction of a satisfaction argument for the security of a system. The process starts with the enumeration of security goals based on assets in the
Haley, Charles B. +3 more
core
ViSpec: A graphical tool for elicitation of MTL requirements
, 2015 One of the main barriers preventing widespread use of formal methods is the elicitation of formal specifications. Formal specifications facilitate the testing and verification process for safety critical robotic systems. However, handling the intricacies
Fainekos, Georgios +2 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Provoking creativity: Imagine what your requirements could be like [PDF]
, 2004 Requirements engineering research, with its focus on elicitation, analysis and management, offers little to support the creation or invention of requirements.
Gizikis, A., Maiden, N., Robertson, S.
core +1 more source