Results 91 to 100 of about 7,965,717 (326)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Agile Requirements Engineering: A systematic literature review
Comput. Stand. Interfaces, 2017 Nowadays, Agile Software Development (ASD) is used to cope with increasing complexity in system development. Hybrid development models, with the integration of User-Centered Design (UCD), are applied with the aim to deliver competitive products with a ...
Eva-Maria Schön +2 more
semanticscholar +1 more source
A Systematic Mapping Study on Security in Agile Requirements Engineering [PDF]
EUROMICRO Conference on Software Engineering and Advanced Applications, 2018 [Background] The rapidly changing business environments in which many companies operate is challenging traditional Requirements Engineering (RE) approaches. This gave rise to agile approaches for RE.
Hugo Villamizar +3 more
semanticscholar +1 more source
Web Services as Product Experience Augmenters and the Implications for Requirements Engineering: A Position Paper [PDF]
, 2004 There is currently little insight into what requirement engineering for web services is and in which context it will be carried out. In this position paper, we investigate requirements engineering for a special kind of web services, namely web services ...
Eck, Pascal van, Wieringa, Roel
core +1 more source
Exact Requirements Engineering for Developing Business Process Models
, 2017 Process modeling is a suitable tool for improving the business processes. Successful process modeling strongly depends on correct requirements engineering.
Nosrati, Masoud
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
On Evidence-based Risk Management in Requirements Engineering
, 2017 Background: The sensitivity of Requirements Engineering (RE) to the context makes it difficult to efficiently control problems therein, thus, hampering an effective risk management devoted to allow for early corrective or even preventive measures ...
B Boehm +15 more
core +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source