Results 91 to 100 of about 6,871,110 (300)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Engineering and management of information modeling requirements

open access: yesTema, 2019
The presented document discusses the application of Requirements Engineering and Management methods and techniques for identification and traceability of requirements to support Information Modelling during the design process.
Giuseppe Martino Di Giuda   +4 more
doaj   +1 more source

Tools for Requirements Engineering

open access: yesIEEE Software
Requirements engineering needs a good process and the right tool. Yet in many companies I observe unsuitable use of tools. Missing, wrong, and changing requirements are major failure points. Tools for requirements facilitate professional and efficient engineering throughout the lifecycle.
Juan Manuel Carrillo de Gea   +5 more
openaire   +3 more sources

A systematic literature review of requirements engineering education. [PDF]

open access: yesRequir Eng, 2023
Daun M   +3 more
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

An engineering design knowledge reuse methodology using process modelling [PDF]

open access: yes, 2007
This paper describes an approach for reusing engineering design knowledge. Many previous design knowledge reuse systems focus exclusively on geometrical data, which is often not applicable in early design stages.
Young, Bob   +9 more
core   +1 more source

Requirements Engineering Quality: a Literature Review

open access: yesJurnal Nasional Pendidikan Teknik Informatika (JANAPATI)
Requirements Engineering Quality (REQ) has a large influence on the success of a software project. A systematic literature review (SLR) is conducted to get complete information about REQ.
Rosa Delima, Azhari, Khabib Mustofa
doaj   +1 more source

Philanthropic conference-based requirements engineering in time of pandemic and beyond. [PDF]

open access: yesRequir Eng, 2023
Levy M   +10 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy