Results 71 to 80 of about 363,478 (268)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Characterizing Efficacy of Alternative Media for Requirements Expression

open access: yesSystems
Requirements are most commonly expressed in natural language, but alternative media can be employed. Previous research has established the viability of model diagrams and engineering drawings for requirements expression.
Jason Kolligs, Lawrence Dale Thomas
doaj   +1 more source

Philanthropic conference-based requirements engineering in time of pandemic and beyond. [PDF]

open access: yesRequir Eng, 2023
Levy M   +10 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Temporal dynamics of requirements engineering from mobile app reviews. [PDF]

open access: yesPeerJ Comput Sci, 2022
Alves de Lima VM   +2 more
europepmc   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Requirements Engineering Quality: a Literature Review

open access: yesJurnal Nasional Pendidikan Teknik Informatika (JANAPATI)
Requirements Engineering Quality (REQ) has a large influence on the success of a software project. A systematic literature review (SLR) is conducted to get complete information about REQ.
Rosa Delima, Azhari, Khabib Mustofa
doaj   +1 more source

Model-Based Requirements Management in Gear Systems Design Based On Graph-Based Design Languages

open access: yesApplied Sciences, 2017
For several decades, a wide-spread consensus concerning the enormous importance of an in-depth clarification of the specifications of a product has been observed. A weak clarification of specifications is repeatedly listed as a main cause for the failure
Kevin Holder   +6 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Home - About - Disclaimer - Privacy