Results 141 to 150 of about 1,301,492 (295)

Just a Paycheck? Assessing Student Benefits of Work on Faculty Research Projects [PDF]

The benefits that students gain from designing and implementing their own independent undergraduate research projects is often presented as a valuable step in their academic career, and a stepping stone to graduate school success.
Mathews, Leah Greden
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Scoping review of community health participatory research projects in Ghana. [PDF]

Glob Health Action, 2022
Kretchy IA, Okoibhole LO, Sanuade OA, Jennings H, Strachan DL, Blandford A, Agyei F, Asante P, Todowede O, Kushitor M, Adjaye-Gbewonyo K, Arhinful D, Baatiema L, Baatiema L, Dankyi E, Grijalva-Eternod CS, Fottrell EF, de-Graft Aikins A.   +17 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Questionnaires and risk scores: how to transform research projects into practical tools. [PDF]

J Bras Pneumol, 2023
Fernandes FLA.
europepmc   +1 more source

CONGRUENCE OF THE HATCH FUNDED REGIONAL RESEARCH PORTFOLIO WITH NATIONAL AND REGIONAL RESEARCH PRIORITIES [PDF]

The major focus of this report is on evaluation of the extent to which the allocation of regional research funding support, particularly the allocation of Hatch Regional Research Funds (RRF), is congruent with national and regional research priorities ...
Halbach, Daniel Walter, Sundquist, W. Burt   +1 more
core   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Research Projects [PDF]

, 1982

core   +3 more sources

Developing the next generation of renewable energy technologies: an overview of low-TRL EU-funded research projects. [PDF]

Open Res Eur, 2023
Pérez Caballero LM, Neira D'Angelo F, Tschentscher R, Gottschalk A, Salem AM, Carbonell D, Dudita-Kauffeld M, Bruch A, Alamaro E, Pasquini L, Ceroni P, Grozdanova A, Privitera S, Vermang B, Schulz P, Mencarelli D, Pierantoni L, Midrio M, Leithead W, Gurruchaga I, Haberl R, Vermaut J, Kauffeld M.   +22 more
europepmc   +1 more source