Results 161 to 170 of about 14,722,971 (292)

Progress in the research and development of oncolytic virus therapies. [PDF]

Front Pharmacol
Li Y, Qin X, Liang C, Wang L.
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Artificial intelligence-driven drug discovery: a deep learning paradigm shift in pharmaceutical research and development. [PDF]

Front Pharmacol
Bi X, Wang Y, Wang J, Liu C.
europepmc   +1 more source

Two thousand and fourteen [2014] Annual Symposium : Reflections on Priorities for Development Policy Research in Cambodia

, 2015
This report summarises the key messages of 30 presentations with implications for research policy and practice under six key themes: economy, agriculture, natural resources, health, education and the ASEAN Economic Community (AEC).
Madhur, Srinivasa
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Correction: Vaccine equity in Africa: a rapid review of policy, legal and governance frameworks to improve research and development. [PDF]

Front Health Serv
Frontiers Production Office.
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

How do nurse educators experience leading research and development projects? A qualitative study in Turkish universities. [PDF]

BMJ Open
Ordu Y, Çiftçi B.
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Editorial: Thymus research and development: a new look at the past, current knowledge, and future perspectives. [PDF]

Front Immunol
Shichkin VP, Shinzawa M, Filipp D, Antica M, Delfino DV.   +4 more
europepmc   +1 more source