Results 41 to 50 of about 51,586,577 (251)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
THE MODEL OF FORMATION OF RESEARCH COMPETENCE OF FUTURE SOFTWARE ENGINEERS
Ìнформаційні технології в освіті, 2014 The article analyzes the practical experience, theoretical and methodological backgrounds toformation of research competence of future software engineers.
N. Osipova, M. Vinnik, Yu. Tarasich
doaj
USING COACHING TECHNOLOGIES IN THE COURSE OF FORMATION OF FUTURE DOCTORS’ OF PHILOSOPHY RESEARCH COMPETENCE IN THE CONDITIONS E-POSTGRADUATE STUDIES [PDF]
Вісник Університету імені Альфреда Нобеля. Серія Педагогіка і психология, 2019 The quality of modern education is determined by the nature of innovative processes as defined by the features of innovations and innovative potential of the educational environment at the institutions of higher education.
Iryna V. Oliynik
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
BUILDING RESEARCH COMPETENCE OF PHD STUDENTS: AN ANALYSIS OF EXPERIENCE OF A PHD SCHOOL
Образование и наука, 2018 Introduction. Postgraduate education of the Russian higher school is traditionally considered as a strategic reserve, which provides the continuity of academic and teaching personnel and the efficiency of education of future experts.
T. А. Strokova
doaj +1 more source
FACTORS AFFECTING RESEARCHERS PERFORMANCE IN THE INDONESIAN INSTITUTE OF SCIENCES
Jurnal Aplikasi Manajemen, 2020 The Performance of Indonesian researchers is relatively low at the international and ASEAN levels. Moreover, LIPI (Indonesian Institute of Sciences) as one of the largest research institutions in Indonesia, its ranks on webometrics continue to decline ...
Sabrul Wasfi, Heti Mulyati, Joko Purwono
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Brazilian Research on Moral Competence
Lawrence Kohlberg introduced the concept of moral judgment competence in his doctoral thesis, which refers to the ability to make judgments based on principles and act accordingly.
Bataglia, Patricia Unger Raphael [UNESP]
core +1 more source