Results 61 to 70 of about 51,586,577 (251)

Cultural competence – transforming policy, services, programs and practice [PDF]

open access: yes, 2014
This chapter discusses some of the complex issues surrounding the notion of cultural competence—and the critical need for practitioners to develop knowledge, skills, understandings and attributes to be responsive in diverse cultural settings.
Roz Walker   +5 more
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Formation of higher educational institution students’ research competence in the light of FGOS of new generation requiremens

open access: yesPolylinguality and Transcultural Practices, 2014
The article is devoted to a problem of formation of higher education institution students’ research competence according to the standard of new generation requirements.
R A Arzumanova
doaj  

METHODICAL MAINTENANCE SYNERGISTIC AND RATIONAL APPROACHS TO TEACHING CHEMISTRY IN HIGH SCHOOL

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2016
At present, we can say the search for new forms and methods of teaching. The most important area of research is to create a teaching environment that allows to realize the goal of building an effective learning process, contributing to the development of
Sergey Alexsandrovich Zolotykhin
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Diseño de estrategia pedagógica para el desarrollo de la competencia investigativa del médico en especialización en medicina general integral Design of pedagogic strategy for the development of research competence of the physician in comprehensive general medicine specialty

open access: yesMedisan, 2012
La universidad debe preservar, desarrollar y promover la cultura de la humanidad a través de sus procesos sustantivos y vínculo con la sociedad, lo cual puede lograr a través de la investigación científica, que constituye además una función esencial de ...
Nilia Victoria Escobar Yéndez   +2 more
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

SCIENTIFIC RESEARCH PRACTICE IN EDUCATIONAL PROGRAMS FOR THE TRAINING OF MASTERS OF PHILOLOGY

open access: yesНеперервна професійна освіта: теорія та практика, 2022
Research practice as a component of the educational programs of the specialty «Philology» at the master's degree in higher education is analyzed, namely its place in the system of specialists' research skills formation.
Iryna Prozhohina
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

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