Results 141 to 150 of about 7,390,753 (310)

Arts Funding Snapshot: GIA's Annual Research on Support for Arts and Culture, 2012 [PDF]

open access: yes, 2012
Includes: Foundation Grants to Arts and Culture, 2010: A One-year Snapshot, and Public Funding for the Arts: 2012 ...
Reina Mukai   +2 more
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

The Depathologising University

open access: yesScandinavian Journal of Disability Research
It has been argued that the university needs depathologising, a radical rethink and reorientation of the university’s relationship with disability. This paper offers an original affirmative proposition: that the university is already depathologising ...
Dan Goodley   +2 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

The intersection of promotion policies, research habitus, and capital distribution: a qualitative case study of two higher education contexts in the United Arab Emirates

open access: yesFrontiers in Education
IntroductionCareer advancement must be based on merit, according to the universal norm. However, faculty members continue to express their dissatisfaction with the existing promotion policies and practices, highlighting issues like ambiguity, lack of ...
Ahmed Elhakim
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Embedding Research Culture in Community Hospitals. [PDF]

open access: yesIntern Med, 2022
Iwata H   +3 more
europepmc   +1 more source

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