Results 51 to 60 of about 811,269 (302)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Knowledge Access through Libraries in the United Digital Market

open access: yesDigital Presentation and Preservation of Cultural and Scientific Heritage, 2022
The European Open Science Cloud and the strategy for unified digital market are corner stones in the way of Europe's economy, industry, and society to the new digital era.
Eliza Stefanova, Krassen Stefanov
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Research Data Alliance (RDA) and the Social Sciences

open access: yes, 2021
The Research Data Alliance (RDA, www.rd-alliance.org) is an international organization aiming to develop infrastructure and community activities that enable open sharing of data. The RDA operates across the globe and connects research data experts (like researchers, data stewards, librarians and funders) from a variety of disciplines, including the ...
openaire   +2 more sources

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

The Research Data Alliance and the Humanities

open access: yes, 2019
The goal of this report is to provide a broad overview of the way the Research Data Alliance (RDA) and the humanities as an academic discipline can be of value to each other. The intended audience for this report in the first instance are digital humanities researchers and service providers in the humanities domain.
openaire   +4 more sources

Optimality and robustness in multi-robot path planning with temporal logic constraints [PDF]

open access: yes
In this paper we present a method for automatically generating optimal robot paths satisfying high-level mission specifications. The motion of the robot in the environment is modeled as a weighted transition system.
Belta, Calin   +4 more
core   +1 more source

The Research Data Alliance

open access: yes, 2016
To appear in the proceedings of Astronomical Data Analysis Software and Systems XXV (ADASS XXV), a conference held 25-29 October 2015 at Sydney, Australia. Edited by N. P. F. Lorente, & K. Shortridge (San Francisco: ASP)
openaire   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

The research data alliance – A global collaboration forum to tackle data challenges

open access: yes, 2021
ABSTRACT / INTRODUCTIONThe Research Data Alliance (RDA) [1], a community-driven initiative with the goal of building the social and technical infrastructure to enable open sharing and re-use of data, currently has over 11,000 members - including data scientists, librarians, researchers, funders, policy makers - from more than 140 countries [2].
Kethers, Stefanie, Treloar, Andrew
openaire   +1 more source

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