Results 61 to 70 of about 811,269 (302)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Impact of Partner Fit and Conflict Management on Alliance Performance In Indonesian Construction Companies

Journal of Business and Social Review in Emerging Economies, 2015
Objective: The purpose of this paper is to investigate the alliance performance of construction companies. A conceptual model is proposed where alliance performance is influenced by a two-dimensional construct composed of the partner fit and conflict ...
Dicky Hida Syahchari, Ruswiati Suryasaputera, Moh. Azlan B. Yahya   +2 more
doaj   +1 more source

Research Data Alliance Hybridisation of Plenaries

, 2023
This document outlines detailed processes to assist with planning hybrid events. The document includes reflections and definitions of what a hybrid event looks like and what to expect during the planning preparation. It covers online and in-person arrangement elements.
Hope, Irina, Bustamente, Alejandra, Underwood, Meghan   +2 more
openaire   +1 more source

Alliance chain-based simulation on a new clinical research data pricing model

Annals of Translational Medicine, 2022
Multicenter clinical research faces many challenges, including how to quantitatively evaluate the data contribution of each research center. However, few data pricing model meets the requirements to the scenario. Thus, a suitable mechanism to measure the data value for clinical research is required.Extensive documents were acquired and analyzed ...
Li, Jing, Wang, Dejian, Qi, Guoqiang, Li, Zheming, Huang, Jian, Zhu, Zhu, Shen, Chen, Lin, Bo, Dong, Kexiong, Zhao, Baolong, Shu, Qiang, Yin, Jianwei, Yu, Gang   +12 more
openaire   +2 more sources

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

The research data alliance: Implementing the technology, practice and connections of a data infrastructure [PDF]

Bulletin of the American Society for Information Science and Technology, 2013
AbstractEditor's SummaryWith research in demand for innumerable applications to society's challenges, the Research Data Alliance (RDA) was formed to create and implement a unified data infrastructure. Established in March 2013, the alliance is directed toward establishing a framework to serve social and technical research needs at the local and global ...
openaire   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Scientific Knowledge Mobilization: Co-evolution of Data Products and Designated Communities

International Journal of Digital Curation, 2015
Digital data are accumulating rapidly, yet issues relating to data production remain unexamined. Data sharing efforts in particular are nascent, disunited and incomplete.
Karen S. Baker, Ruth E. Duerr, Mark A. Parsons   +2 more
doaj   +1 more source

Introducing the FAIR Principles for research software

Scientific Data, 2022
Research software is a fundamental and vital part of research, yet significant challenges to discoverability, productivity, quality, reproducibility, and sustainability exist.
Michelle Barker, Neil P. Chue Hong, Daniel S. Katz, Anna-Lena Lamprecht, Carlos Martinez-Ortiz, Fotis Psomopoulos, Jennifer Harrow, Leyla Jael Castro, Morane Gruenpeter, Paula Andrea Martinez, Tom Honeyman   +10 more
doaj   +1 more source

Effect of volcanic dykes on coastal groundwater flow and saltwater intrusion : a field-scale multiphysics approach and parameter evaluation [PDF]

Acknowledgments This research was primarily based on research grant‐aided by the Irish Department of Communications, Energy and Natural Resources under the National Geoscience Programme 2007–2013.
A. González-Quirós, Abarca, Abdul Nassir, Archie, Arps, Attwa, Babiker, Beaujean, Bense, Berkowitz, Boehmer, Boonstra, Bourhane, Bouwer, Bromley, C. Wilson, Carrera, Comte, Comte, Comte, Cook, Cooper, Cooper, Cronin, Custodio, Dam, Dickson, Dickson, Dogan, Earls, Engel, Engel, Ernst, Erskine, European Commission, Fetter, Günther, Hartley, Healy, Herckenrath, Herckenrath, Izquierdo, J.-C. Comte, Jacob, Kalin, Kirkegaard, Koukadaki, Linde, Marsily, McKinley, McNeill, Mitchell, Moench, Moench, Morel, Neuman, Nguyen, Oldenburg, Parasnis, Perrin, Post, Revil, Rücker, Sami, Si, Simmons, Singhal, Souza, Sultan, Summer, Takasaki, Taylor, U. Ofterdinger, Vittecoq, Vittecoq, Waxman, Werner, Wilkes, Yang, Zheng   +79 more
core   +1 more source