Results 131 to 140 of about 14,201,106 (332)

Proyectos de investigación científica en salud

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
El proceso de investigación científica nace a partir de la necesidad de resolver un déficit cognitivo existente en el objeto de estudio, transita por diferentes etapas, condicionadas por factores objetivos y subjetivos.
Elso Manuel Cruz Cruz
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Research on the Design and Development of the Undergraduate Syllabus of Gauhati University

, 2022
Rashri Duzta, Reshma Khatun, Nasir Ahmed, A Adhikary, Ramanath Gorain, Pargat Garcha, Singh, Sales, Joan Auxiliadora, Rafaela Traver, Garca, Carina Girvan, Claire Conneely, Brendan Tangney   +13 more
openalex   +1 more source

Dimensions of design space: a decision-theoretic approach to optimal research design [PDF]

Bayesian decision theory can be used not only to establish the optimal sample size and its allocation in a single clinical study, but also to identify an optimal portfolio of research combining different types of study design.
Karl Claxton, Stefano Conti
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Rayuela 2.0: Una herramienta para promocionar la labor innovadora de maestros y maestras mediante la generación de diseños de investigación rigurosos / Hopscotch 2.0: A tool to promote teachers’ innovative work through the generation of rigorous research designs

Revista Latinoamericana de Tecnología Educativa, 2019
En este artículo presentamos Rayuela 2.0, un marco teórico y una herramienta web pensados para ayudar a investigadores noveles en educación y ciencias sociales, en la generación de diseños de investigación sólidos y bien informados.
Iván Manuel Jorrín-Abellán
doaj   +1 more source

A Design Archival Approach to Knowledge Production in Design Research and Practice [PDF]

, 2019
Bondarenko O., Brandt E., Fritsch J., Gaver W., Höök K., Iversen O.S., Stolterman E.   +6 more
core   +1 more source

Analytical and scale model research aimed at improved hangglider design [PDF]

, 1979
Research consisted of a theoretical analysis which attempts to predict aerodynamic characteristics using lifting surface theory and finite-element structural analysis as well as an experimental investigation using 1/5 scale elastically similar models in ...
Chang, L. S., Kroo, I.
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

La investigación educativa en Venezuela: un análisis bibliográfico A pesquisa educativa na Venezuela: uma análise bibliográfica Educational Research in Venezuela: A Literature Review

Educación y Educadores, 2011
El texto da a conocer la estructuración de resúmenes de artículos científicos publicados basado en una línea de investigación en discurso académico de la educación, para ser más específico con géneros textuales relevantes de este ámbito.
Carlos Eduardo Blanco, Luisa Elena García   +1 more
doaj