A Research Domain Criteria (RDoC)-Guided Dashboard to Review Psilocybin Target Domains: A Systematic Review. [PDF]
Background Preliminary results from randomized controlled studies as well as identified molecular, cellular, and circuit targets of select psychedelics (e.g., psilocybin) suggest that their effects are transdiagnostic.
Pouyan N +16 more
europepmc +3 more sources
Emotional Responses (Intensity/Valence) Fulfill RDoC Criteria but Remain Excluded From Diagnostic Classifications of Mood Disorders. [PDF]
ABSTRACT Objectives Categorical classifications of depression, such as DSM‐5 and ICD, are limited by high clinical heterogeneity, arbitrary diagnostic thresholds, and weak links to underlying pathophysiology. In line with the Research Domain Criteria (RDoC) framework, this article proposes a dimensional and mechanistic approach centered on emotional ...
Henry C +4 more
europepmc +2 more sources
Nomenclature for mental disorder was updated in 2013 with the publication of the fifth edition of the Diagnostic and Statistical Manual (DSM-5). In DSM-5, substance use disorders are framed as more dimensional. First, the distinction between abuse and dependence is replaced by substance use. Second, the addictions section now covers both substances and
Samantha J, Brooks +3 more
openaire +3 more sources
Making Sense of the Matrix: A Qualitative Assessment and Commentary on Connecting Psychiatric Symptom Scale Items to the Research Domain Criteria (RDoC). [PDF]
The Research Domain Criteria (RDoC) initiative aims to organize research according to domains of brain function. Dysfunction within these domains leads to psychopathology that is classically measured with rating scales.
Citrome L +9 more
europepmc +3 more sources
Using Development and Psychopathology Principles to Inform the Research Domain Criteria (RDoC) Framework. [PDF]
AbstractIn 2010, the Research Domain Criteria (RDoC) were developed to advance our understanding of the pathophysiology of mental illness across multiple levels of analysis, ranging from cells to circuits to self-report instruments. Several conceptual RDoC-informed manuscripts have highlighted the importance of studying how developmental processes give
Conradt E, Crowell SE, Cicchetti D.
europepmc +4 more sources
IntroductionWhile a growing body of research is adopting Research Domain Criteria (RDoC)-related methods and constructs, there is still a lack of comprehensive reviews on the state of published research on Positive Valence Systems (PVS) and Negative ...
Sarah Jane Böttger +9 more
doaj +1 more source
Understanding Suicide Risk within the Research Domain Criteria (RDoC) Framework: Insights, Challenges, and Future Research Considerations. [PDF]
Suicide is a leading cause of death worldwide. Prior research has focused primarily on sociodemographic and psychiatric risk factors with little improvement in the prediction or prevention of suicidal behavior over time.
Glenn CR, Cha CB, Kleiman EM, Nock MK.
europepmc +2 more sources
Integrating NIMH Research Domain Criteria (RDoC) into Depression Research. [PDF]
The NIMH Research Domain Criteria (RDoC) initiative grew out of the agency's goal to develop "new ways of classifying mental disorders based on behavioral dimensions and neurobiological measures" (NIMH, 2008). In this article, we review how depression research can be meaningfully conducted within an RDoC framework, with a particular focus on the ...
Woody ML, Gibb BE.
europepmc +4 more sources
Revisiting the seven pillars of RDoC
Background In 2013, a few years after the launch of the National Institute of Mental Health’s Research Domain Criteria (RDoC) initiative, Cuthbert and Insel published a paper titled “Toward the future of psychiatric diagnosis: the seven pillars of RDoC.”
Sarah E. Morris +5 more
doaj +1 more source
Psychiatry and the Sociology of Novelty: Negotiating the US National Institute of Mental Health "Research Domain Criteria" (RDoC). [PDF]
In the United States, the National Institute of Mental Health (NIMH) is seeking to encourage researchers to move away from diagnostic tools like the Diagnostic and Statistical Manual of Mental Disorders (the DSM).
Pickersgill M.
europepmc +2 more sources

