Results 131 to 140 of about 841,358 (341)
Research Ethics Committees: Adaptation to The New European Regulation of Clinical Trials – A Viewpoint From Germany [PDF]
, 2015 Joerg Hasford
openalex +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Can an ethics officer role reduce delays in research ethics approval? A mixed-method evaluation of an improvement project. [PDF]
, 2016 OBJECTIVE: Frustration continues to be directed at delays in gaining approvals for undertaking health research in the UK. We aimed to evaluate the impact of an ethics officer intervention on rates of favourable opinions (approval) and provisional ...
Al-Shahi Salman, Rustam +5 more
core +2 more sources
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Informed consent to HIV cure research [PDF]
, 2017 Trials with highly unfavourable risk–benefit ratios for participants, like HIV cure trials, raise questions about the quality of the consent of research participants.
Bromwich, Danielle, Millum, Joseph R.
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
MedEdPublish, 2016 Usage of and investment in e-learning has also grown in the field of research ethics. There are currently several distance capacity building programs on this theme, although few are translated to the language and adapted to the legislation of countries ...
Pollyana Gontijo +3 more
doaj
Research ethics committees : a short systematic study of national and international literature [PDF]
, 2013 Indrodução: No Brasil, a efetivação dos Comitês de Ética em Pesquisas (CEPs) ocorreu com a Resolução 196/96 do Conselho Nacional de Saúde (CNS), cuja publicação despertou interesse de estudos sobre a aplicação de suas diretrizes e atuação dos CEPs ...
Araujo, Tereza Cristina Cavalcanti Ferreira de +1 more
core
Observational study of 353 applications to London multicentre research ethics committee 1997-2000 [PDF]
, 2002 Malcolm Boyce
openalex +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source