Results 81 to 90 of about 841,358 (341)

Ethical challenges in cross-cultural field research: a comparative study of UK and Ghana [PDF]

, 2015
YesResearch ethics review by ethics committees has grown in importance since the end of the Nuremberg trials in 1949. However, ethics committees have come under increasing criticisms either for been ‘toothless or too fierce’ (Fistein & Quilligan, 2012 ...
Adu-Gyamfi, Jones
core   +1 more source

Ethical review and children’s research in Ireland. [PDF]

, 2010
A substantial increase in research into the lives of children has been experienced over the last 20 years in many countries, including Ireland. This increase is not only in the amount of research undertaken, but also in the multidisciplinary range of ...
Felzmann, Heike, Ni Chonnachtaigh, Sorcha, Nic Gabhainn, Saoirse, O’Higgins, Siobhan, Sixsmith, Jane   +4 more
core   +1 more source

Research ethics committees in the regulation of clinical research: comparison of Finland to England, Canada, and the United States

Health Research Policy and Systems, 2016
BackgroundThe aim of this paper is to compare common features and variation in the work of research ethics committees (RECs) in Finland to three other countries – England, Canada, the United States of America (USA) – in the late 2000s.MethodsSeveral ...
E. Hemminki
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Surveying the Indian research ethics committee response to the COVID‐19 pandemic [PDF]

, 2023
Yashashri C. Shetty, Sudha Ramalingam, Paresh G Koli, Karthikeyan Shanmugam, Rajmohan Seetharaman   +4 more
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Research ethics capacity building in Sub-Saharan Africa: a review of NIH Fogarty-funded programs 2000–2012 [PDF]

, 2014
The last fifteen years have witnessed a significant increase in investment in research ethics capacity development throughout the world. We examine nine research ethics training programs that are focused on Sub-Saharan Africa and supported by the US ...
Adebamowo, Clement, Benatar, Solomon, Fleischer, Theodore, Hyder, Adnan A., Kass, Nancy, Kruger, Mariana, Meslin, Eric M., Ndebele, Paul, Wassenaar, Douglas   +8 more
core   +1 more source

Heterogeneity of Human Research Ethics Committees and Research Governance Offices across Australia: An observational study.

Australasian Medical Journal, 2016
BACKGROUND Conducting ethically grounded research is a fundamental facet of all investigations. Nevertheless, the administrative burdens of current ethics review are substantial, and calls have been made for a reduction in research waste.
E. De Smit, L. Kearns, Linda Clarke, J. Dick, C. Hill, A. Hewitt   +5 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Readability of informed consent documents and its impact on consent refusal rate

Perspectives in Clinical Research
Introduction: Informed consent documents (ICDs) are integral to a research project and must provide all required information to the participant. We undertook a 6-year retrospective cross-sectional analysis of ICDs to assess the same. Methods: We accessed
Yash V. Kamath, Yashashri C. Shetty, Ishita C. Lanjewar, Ankita Kulkarni   +3 more
doaj   +1 more source