Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Assessing the Impact of Game Day Schedule and Opponents on Travel Patterns and Route Choice using Big Data Analytics [PDF]
, 2019 The transportation system is crucial for transferring people and goods from point A to point B. However, its reliability can be decreased by unanticipated congestion resulting from planned special events. For example, sporting events collect large crowds
Ahsani, Vesal, Sharma, Anuj
core +1 more source
Spatial and temporal hot spots of Aedes albopictus abundance inside and outside a South European metropolitan area [PDF]
, 2016 Aedes albopictus is a tropical invasive species which in the last decades spread worldwide, also colonizing temperate regions of Europe and US, where it has become a public health concern due to its ability to transmit exotic arboviruses, as well as ...
Caputo, Beniamino +8 more
core +4 more sources
Visualization Analysis of Subsurface Drip Irrigation Research Based on CiteSpace
Guan'gai paishui xuebao, 2023 【Objective】 The development and application of subsurface drip irrigation is of great importance for helping mitigate the limitation of water resources faced by agriculture in arid and semiarid regions around the world.
WEI Qi +6 more
doaj +1 more source
Research hotspots and future trends of hot corrosion research: a bibliometric analysis
RSC Advances, 2023 Knowledge map of hot corrosion research: six research hotspots of the hot corrosion research field were elucidated.
Andrieanto Nurrochman +4 more
openaire +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Characterization of mutations and loss of heterozygosity of p53 and K-\u3ci\u3eras\u3c/i\u3e2 in pancreatic cancer cell lines by immobilized polymerase chain reaction [PDF]
, 2003 Background The identification of known mutations in a cell population is important for clinical applications and basic cancer research. In this work an immobilized form of the polymerase chain reaction, referred to as polony technology, was used to ...
Butz, James +2 more
core +1 more source
Frontiers in Environmental Science, 2022 Research on greenhouse gas (GHG; CO2, CH4, N2O) emissions from hydropower reservoirs has attracted widespread attention due to the potential effect on global climate change.
Yadi Ai +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Hotspots: Modelling capacity for vector-borne disease risk analysis in New Zealand: A case study of Ochlerotatus camptorhynchus incursions in New Zealand [PDF]
, 2005 This Hotspots case study of Oc. camptorhynchus in New Zealand forms part of the wider aims and objectives of the Hotspots project. The overall aims of the case study were: 1. To evaluate the performance of the Hotspots model as a risk analysis tool for
de Wet, Neil +4 more
core +1 more source