Results 111 to 120 of about 1,472,859 (309)

Teaching research integrity : a manual of good practices

This article addresses the critical need for effective teaching strategies in research integrity (RI), acknowledging widespread uncertainty among educators on the best approach.
Priess-Buchheit, Julia, Blom, Fenneke, Groenink, Lucianne, Ristic, Dragana Ignjatovic, Asaduzzaman, Muhammad, Iphofen, Ron, Gruber, Bernadette, Achermann, Gerald, Salwén, Håkan,, van den Hoven, Mariëtte, Salwen, Hakan, Dwojak-Matras, Agnieszka, Holm, Cyril   +12 more
core   +1 more source

XML Data Integrity Based on Concatenated Hash Function [PDF]

, 2009
Data integrity is the fundamental for data authentication. A major problem for XML data authentication is that signed XML data can be copied to another document but still keep signature valid. This is caused by XML data integrity protecting.
Lu, Joan, Yip, YJ, Liu, Baolong, Lu, J, Liu, B, Yip, Yau Jim   +5 more
core  

Vibration fatigue comparative test and life prediction for titanium alloy connection structures

Hangkong gongcheng jinzhan
A large number of mechanical connection structures in aircraft face vibration fatigue problems，and the evaluation of vibration fatigue performance is the key to determine the service life，safety design and evaluation of the structure.
HE Shi, LIU Xiaochuan, LIU Haihan, LI Kaixiang, BAI Chunyu   +4 more
doaj   +1 more source

Big Research Data Integration

, 2019
The paper presents a vision about a new paradigm of data integration in the context of the scientific world, where data integration is instrumental in exploratory studies carried out by research teams. It briefly overviews the technological challenges to be faced in order to successfully carry out the traditional approach to data integration.
Bartalesi Lenzi V, Meghini C, Thanos C
openaire   +3 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Research on influence law of circuit parameters on heating characteristics of graphite heating elements

Hangkong gongcheng jinzhan
Circuit parameters are the decisive factors for the heating performance of graphite heating elements，and the research on the influence of circuit parameters is the basis for the design of high-performance and high-reliability graphite heaters.
LI Junpeng, LI Shiping, WANG Zhenya, CONG Linhua, WU Jingtao   +4 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Attitudes and knowledge on research integrity among first- and second-year research postgraduate students in HKU

, 2017
As part of the coursework training for basic knowledge on research skills and methods, all MPhil and 4-year PhD students in HKU are required to pass a faculty-based research ethics course by the end of the probationary period (i.e.
Leung, FKS
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source