Results 121 to 130 of about 21,392,268 (380)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Precision Extrusion Deposition of Polycaprolactone/Hydroxyapatite Tissue Scaffolds [PDF]
, 2006 Freeform fabrication provides an effective process tool to manufacture advanced tissue scaffolds with specific designed properties. Our research focuses on using a novel Precision Extrusion Deposition (PED) process technique to directly fabricate ...
Güçeri, S., Shor, L., Sun, W.
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
An Approach to Using Non Safety-Assured Programmable Components in Modest Integrity Systems [PDF]
, 2010 Programmable components (like personal computers or smart devices) can offer considerable benefits in terms of usability and functionality in a safety-related system.
Bishop, P. G., Chozos, N., Tourlas, K.
core +1 more source
The Hong Kong Principles for assessing researchers: Fostering research integrity
PLoS Biology, 2019 For knowledge to benefit research and society, it must be trustworthy. Trustworthy research is robust, rigorous, and transparent at all stages of design, execution, and reporting.
D. Moher +8 more
semanticscholar +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Proceedings of the Workshop on Versioning in Hypertext Systems [PDF]
, 1995 This report contains 9 papers presented at a workshop on version management and hypertext, as well as a summary introduction by the organizers. These papers address requirements, solutions, and research issues related to the management of hypertext ...
Durand, David +3 more
core +1 more source
Burton Clark's half century: selected writings 1956-2006 [PDF]
, 2010 The work of Burton Clark extended over more than half a century - and also from its original base in sociology to embrace wider inter-disciplinary studies. His identification of the major research themes in higher education continues to be valid, despite
Scott, Peter
core +5 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Research progress of ultrasonic in-situ nondestructive testing technology for aircraft structure
Journal of Aeronautical MaterialsDamage detection is a critical link of aviation equipment development，field operation and maintenance，which directly affects the development process and service safety of aircraft structure.
ZHANG Wei +4 more
doaj +1 more source