Results 71 to 80 of about 1,472,859 (309)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Secure agent data integrity shield

, 2004
In the rapidly expanding field of E-Commerce, mobile agent is the emerging technology that addresses the requirement of intelligent filtering/processing of information. This paper will address the area of mobile agent data integrity protection.
Yang, Y., Guan, SU, Yang, Y, Guan, S.-U.
core   +1 more source

Development and Field Test of Integrated Electronics Piezoelectric Accelerometer Based on Lead-Free Piezoelectric Ceramic for Centrifugal Pump Monitoring

Sensors
In this study, an Integrated Electronics Piezoelectric (IEPE)-type accelerometer based on an environmentally friendly lead-free piezoceramic was fabricated, and its field applicability was verified using a cooling pump owned by the Korea Atomic Energy ...
Byung-Hoon Kim, Dae-Sic Jang, Jeong-Han Lee, Min-Ku Lee, Gyoung-Ja Lee   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Alternative patch repair materials for rebar corrosion damage

MATEC Web of Conferences, 2018
One of the most common methods adopted in the rehabilitation of corrosion-damaged concrete is the patch repair procedure. However, in practice this method has shown to often be unreliable as a consequence of the widespread occurrence of shrinkage induced
Jassa Primesh, Beushausen Hans, Tchetgnia Ngassam Ines   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Policy on Research Misconduct

, 2011
Ethic
Office of the Vice President for Research
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Impact of land-use and fecal contamination on Escherichia populations in environmental samples

Scientific Reports
Understanding the composition of complex Escherichia coli populations from the environment is necessary for identifying strategies to reduce the impacts of fecal contamination and protect public health.
Adrian L. Cookson, Jonathan C. Marshall, Patrick J. Biggs, Lynn E. Rogers, Rose M. Collis, Megan Devane, Rebecca Stott, Gale Brightwell   +7 more
doaj   +1 more source

Failure Analysis of Large-Scale Composite Fuselage Panels Under Combined Loads

Aerospace
The fuselage serves as the primary component of commercial aircraft. The strength reliability of fuselage panels is therefore crucial for commercial aircraft.
Fei Yuan, Liping Cheng, Xiangming Chen, Lei Li, Fei Yu, Yanan Chai   +5 more
doaj   +1 more source