Results 91 to 100 of about 355,754 (301)

Assessing the impact of armed conflict on the progress of achieving 17 sustainable development goals

open access: yesiScience
Summary: With global armed conflicts reaching a 30-year high in 2023, understanding their impact on the progress of Sustainable Development Goals (SDGs) is crucial.
Di Wang   +3 more
doaj  

Multiple Methods, Communicative Preferences and the Incremental Interview Approach Protocol

open access: yesForum: Qualitative Social Research, 2009
This article introduces a multiple methods data collection protocol. The protocol has been designed mainly for those unsure of the practical steps needed to insure coherent data-sets with respect to the substantive, theoretical and methodological issues ...
David M. Hoffman
doaj  

Do You See what I See? Tracking the Perceptual Beliefs of Robots

open access: yesiScience, 2020
Summary: Keeping track of others' perceptual beliefs—what they perceive and know about the current situation—is imperative in many social contexts. In a series of experiments, we set out to investigate people's ability to keep track of what robots know ...
Sam Thellman, Tom Ziemke
doaj  

Carrying out research across the arts and humanities and social sciences: developing the methodology for Dementia and Imagination [PDF]

open access: hybrid, 2016
Andrew Newman   +10 more
openalex   +1 more source

Critical social science as a research methodology in universities in times of crisis

open access: yesQualitative Research Journal, 2020
PurposeTo consider what a criticalist qualitative research methodology might look like for universities in the context of the contemporary COVID-19 crisis.Design/methodology/approachThis polemical paper explores the rationale for a dramatic recasting of the approach needed in qualitative research methodology to address the challenges of the crisis ...
openaire   +2 more sources

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee   +9 more
wiley   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Observational studies of exposure to tobacco and nicotine products: Best practices for maximizing statistical precision and accuracy

open access: yesiScience
Summary: Non-randomized observational studies can track risk-induction and -reduction associated with real-world use of non-combusted nicotine and tobacco products.
Gal Cohen, Steven Cook
doaj  

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

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