Results 71 to 80 of about 429,366 (262)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Understanding Qualitative Research Methodology: A Systematic Review [PDF]

E-Journal of Humanities, Arts and Social Sciences
As novice researchers and supervisors, the researchers of the current study have noticed that many postgraduate students encounter challenges in understanding qualitative research methodology.
David Seetsa Makateng , Ntsoaki Teresa Mokala   +1 more
doaj   +1 more source

Conceptual and Methodological Research of Xenophobia in Social Sciences

Mediterranean Journal of Social Sciences, 2015
The article presents a conceptual and methodological analysis of xenophobia study in social sciences. In order to investigate the phenomenon of xenophobia, the authors propose to use the methodology of constructive realism that makes it possible to substantiate the social nature of criteria for defining the "outsiders" and their dynamics.
Vladimir Alexandrovich Kirik, Alexander Vladimirovich Popov, Oxana Yuryevna Posukhova, Anton Vladimirovich Serikov, Olga Mikhailovna Shevchenko   +4 more
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Ethical Dilemma and Research Methodology of Social Sciences

Bangladesh Journal of Bioethics, 1970
DOI: http://dx.doi.org/10.3329/bioethics.v1i1.9529 Bangladesh Journal of Bioethics 2010; 1(1 ...
openaire   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Screenathon 2.0: human–AI collaborative screening applied to patient-generated health data

Scientific Reports
Systematic reviews are essential for evidence-based research, yet the traditional screening process is time-consuming and difficult to scale. Human-only screening can introduce inconsistency, while fully automated approaches employing Large Language ...
Jonas Bergmann, Tiago Azzi, Rutger Neeleman, Kianush Monschau, Berke Yazan, Elena Jalsovec, Emily Westerbeek, Felix Weijdema, Jonathan de Bruin, Qixiang Fang, Rens van de Schoot   +10 more
doaj   +1 more source

Challenges of naturalism in social science methodology [PDF]

حکمت و فلسفه
This article examines and discusses the application of naturalistic methodology in social sciences and the challenges facing this methodology. Social science methodology faces a fundamental question; whether the application of natural science methodology
payam fazli
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source