Results 61 to 70 of about 2,566,888 (342)
iScienceSummary: Non-randomized observational studies can track risk-induction and -reduction associated with real-world use of non-combusted nicotine and tobacco products.
Gal Cohen, Steven Cook
doaj +1 more source
The impact of the COVID-19 pandemic on enrollment in undergraduate health-related studies in Spain
BMC Medical Education, 2023 The aim of this study was to determine whether the pandemic has reinforced the choice of pursuing health-related bachelor’s degrees, and to identify underlying factors that could contribute to that impact.
Jaume-Miquel March-Amengual +11 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
LEGAL RESEARCH METHODOLOGY AND THE DREAM OF INTERDISCIPLINARITY [PDF]
, 2013 There are increasing calls for academics to abandon "traditional" disciplinary research and to engage in multi-, inter- and transdisciplinary research.
Irma J Kroeze
core +2 more sources
Expectations guide predictive eye movements and information sampling during face recognition
iScienceSummary: Context information has a crucial impact on our ability to recognize faces. Theoretical frameworks of predictive processing suggest that predictions derived from context guide sampling of sensory evidence at informative locations. However, it is
Annika Garlichs +3 more
doaj +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Use of measurement theory for operationalization and quantification of psychological constructs in systems dynamics modelling [PDF]
, 2016 The analytical tools available to social scientists have traditionally been adapted from tools originally designed for analysis of natural science phenomena.
Ara Yeghiazarian +12 more
core +1 more source
Do You See what I See? Tracking the Perceptual Beliefs of Robots
iScience, 2020 Summary: Keeping track of others' perceptual beliefs—what they perceive and know about the current situation—is imperative in many social contexts. In a series of experiments, we set out to investigate people's ability to keep track of what robots know ...
Sam Thellman, Tom Ziemke
doaj +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source