Results 61 to 70 of about 355,754 (301)

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Impact of social context on human facial and gestural emotion expressions

open access: yesiScience
Summary: Humans flexibly adapt expressions of emotional messages when interacting with others. However, detailed information on how specific parts of the face and hands move in socio-emotional contexts is missing.
Raphaela Heesen   +6 more
doaj  

Integrated Approach in “Social Research of Science” as a Methodological Problem

open access: yesProcedia - Social and Behavioral Sciences, 2015
AbstractSociology of scientific knowledge (SSK) is a study of science as a social activity, especially dealing with the social conditions and effects of science and with the social structures and processes of scientific activity. The theorists of Sociology of Scientific Knowledge consider sociological factors as influencing all beliefs in science ...
openaire   +2 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

The impact of climatic factors on negative sentiments: An analysis of human expressions from X platform in Germany

open access: yesiScience
Summary: Expressions in social media can provide a rapid insight into people’s reactions to events, such as periods of climatic stress. This study explored the link between climatic stressors and negative sentiment on the X platform in Germany to inform ...
Tareq Al-Ahdal   +6 more
doaj  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Advancing health equity in the aftermath of COVID-19: Confronting intensifying racial disparities

open access: yesiScience
Summary: The COVID-19 pandemic has exposed and exacerbated the persistent racial and ethnic health disparities in the United States. The pandemic has also had profound spillover effects on other aspects of health and wellbeing, such as mental health ...
Kristen R. Prentice   +3 more
doaj  

Acculturation and Naturalization: Insights From Representative and Longitudinal Migration Studies in Germany

open access: yesFrontiers in Psychology, 2019
In recent years, Western countries have been experiencing a growing wave of immigration. Due to this development, these countries are facing great challenges in successfully integrating large numbers of immigrants and in preserving social cohesion ...
Débora B. Maehler   +2 more
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

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