Results 61 to 70 of about 1,919,142 (346)

The attractiveness of the project of practical methodology and virtue epistemology for the economic history research [PDF]

, 2017
Ewa Domańska, a distinguished historian of historiography and the methodologist of history, has provided an insightful commentary on the state of humanities and social sciences.
Bębnowski, Damian
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Scale in education research: towards a multi-scale methodology [PDF]

, 2013
This article explores some theoretical and methodological problems concerned with scale in education research through a critique of a recent mixed-method project. The project was framed by scale metaphors drawn from the physical and earth sciences and I
Andrew Noyes, Ball S., Berkes F., Bourdieu P., Bourdieu P., Bourdieu P., Crotty M., Dorling D., Giddens A., Goldstein H., Herod A., Massey D., McKinnon D., Noyes A., Noyes A., Sturman L., Swyngedouw E., Tashakkori A., Tashakkori A., Thrift N.   +19 more
core   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Expectations guide predictive eye movements and information sampling during face recognition

iScience
Summary: Context information has a crucial impact on our ability to recognize faces. Theoretical frameworks of predictive processing suggest that predictions derived from context guide sampling of sensory evidence at informative locations. However, it is
Annika Garlichs, Mark Lustig, Matthias Gamer, Helen Blank   +3 more
doaj   +1 more source

Determining minimum number of valid days for accurate estimation of sedentary behaviour and awake-time movement behaviours using the ActivPAL3 in nursing home residents

European Review of Aging and Physical Activity, 2023
Introduction Scarce evidence is available about the minimum number of valid days wearing the activPAL3 to obtain a precise estimate of sedentary behaviour (SB) and awake-time movement behaviours (ATMB) in nursing home (NH) residents.
Pau Farrés-Godayol, Miguel Ángel Ruiz-Díaz, Philippa Dall, Dawn A. Skelton, Eduard Minobes-Molina, Javier Jerez-Roig, Maria Giné-Garriga   +6 more
doaj   +1 more source

Adolescents from low-income sectors: the challenge of studying in a time of digital environments [PDF]

, 2014
This paper is about practices and perceptions regarding the study of adolescents from low-income sectors in the City of Buenos Aires. The methodology consisted of 26 in-depth interviews with low-income adolescents and participant observations in twenty ...
Linne, Joaquín Walter
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Integration of cognitive tasks into artificial general intelligence test for large models

iScience
Summary: During the evolution of large models, performance evaluation is necessary for assessing their capabilities. However, current model evaluations mainly rely on specific tasks and datasets, lacking a united framework for assessing the ...
Youzhi Qu, Chen Wei, Penghui Du, Wenxin Che, Chi Zhang, Wanli Ouyang, Yatao Bian, Feiyang Xu, Bin Hu, Kai Du, Haiyan Wu, Jia Liu, Quanying Liu   +12 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source