Results 101 to 110 of about 77,403,001 (321)
Sustainability: Science, Practice, & Policy, 2007 Furthermore, I believe that given their head start in being necessarily embedded in complementary studies that cross disciplines, sustainability scientists can, by example, enhance the relevance of their work to that of other disciplines.
Sidney Draggan
doaj
Tracing back primed resistance in cancer via sister cells
Nature CommunicationsExploring non-genetic evolution of cell states during cancer treatments has become attainable by recent advances in lineage-tracing methods. However, transcriptional changes that drive cells into resistant fates may be subtle, necessitating high ...
Jun Dai +19 more
doaj +1 more source
Loss of mtDNA activates astrocytes and leads to spongiotic encephalopathy
Nature Communications, 2018 Astrocytes in the brain are metabolically dynamic. Here, Ignatenko, Chilov and colleagues delete mitochondrial DNA (mtDNA) in a cell type specific manner, and show that inactivation of mtDNA helicase Twinkle in astrocytes leads to spongiotic ...
Olesia Ignatenko +9 more
doaj +1 more source
, 2019 Scholarly studies of international student mobility programs have increased during the last two decades, particularly following the Bologna Declaration.
Achinto Roy +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Forum: Qualitative Social Research, 2013 In this book the epistemologist of the social sciences Ulises TOLEDO NICKELS develops a reconstruction of a number of theoretical, epistemological, and methodological reflections and of the findings of empirical research that, during the 20th century ...
Fernando Farías Olavarría
doaj
SALSA: a regulator of the early steps of complement activation on mucosal surfaces
Frontiers in Immunology, 2016 Complement is present mainly in blood. However, following mechanical damage or inflammation, serous exudates enter the mucosal surfaces. Here the complement proteins interact with other endogenous molecules to keep microbes from entering the parenteral ...
Martin eReichhardt, Seppo eMeri
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
BMC Health Services ResearchBackground New long-acting pre-exposure prophylaxis (LA-PrEP) options offer an alternative to daily oral PrEP, which poses difficulties for adherence, especially during pregnancy and postpartum.
Tessa Concepcion +17 more
doaj +1 more source