Results 101 to 110 of about 4,031,498 (261)
Human pluripotent reprogramming with CRISPR activators
Nature Communications, 2018 CRISPRa is an attractive tool for cellular reprogramming due to its multiplexing capacity and direct targeting of genomic loci. Here the authors demonstrate the reprogramming of human fibroblasts into iPSCs, which is enhanced by targeting a conserved Alu-
Jere Weltner +8 more
doaj +1 more source
Australian Sheep Industry CRC: Economic Evaluations of Scientific Research Programs [PDF]
By the end of its seven-year term in 2007-08, the Australian Sheep Industry CRC (Sheep CRC) will have received total funds of about $90 million, that comprises Commonwealth and industry funding of $30 million, and in-kind contributions valued at $60 ...
Griffith, Garry R. +2 more
core +1 more source
Measuring the Performance of Livability Programs, MTI Report 12-06 [PDF]
, 2013 This report analyzes the performance measurement processes adopted by five large “livability” programs throughout the United States. It compares and contrasts these programs by examining existing research in performance measurement methods.
Fabish, Lisa, Haas, Peter J.
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A natural extension of the methodology of the scientific research programmes of Imre Lakatos [PDF]
Research programs allow the development of more complex theories. The terms can be applied to both individual theories and programs. Unlike Kuhn's scientific revolutions, Lakatos assumed that the simultaneous existence of several research programs is the
Sfetcu, Nicolae
core
Ensuring Success for Children With Incarcerated Parents [PDF]
, 2009 Outlines issues children with incarcerated parents face and suggests strategies for funders to support programs that address their needs, including visiting programs, parenting classes, and mentoring, as well as research, advocacy, and ...
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Foreign technology summary of flight crucial flight control systems [PDF]
, 1984 A survey of foreign technology in flight crucial flight controls is being conducted to provide a data base for planning future research and technology programs.
Rediess, H. A.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
ECONOMIC RESEARCH PROGRAMS FOR COMMUNITY DEVELOPMENT--WHY DO IT? [PDF]
Community/Rural/Urban Development,
Motes, William C.
core +1 more source