Results 71 to 80 of about 10,605,669 (311)

Open-ended design : local re-appropriations through imperfection [PDF]

open access: yes, 2019
Design for Sustainability (DfS) focuses on wicked problems that cannot be modelled in reductionist ways. Furthermore, when bottom-up local interventions prove to have positive effects in their context, they remain hard to spread and might ...
Ostuzzi, Francesca, Rognoli, Valentina
core  

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

From Silos to Synergy: A Serious Game for Cross-Functional Collaboration in Human-Centric Asset Management

open access: yesIEEE Access
Asset Management (AM) is an integrative discipline that relies on expert knowledge from diverse functions to develop holistic and coordinated solutions.
Giacomo Barbieri, Freddy Zapata
doaj   +1 more source

Learning through prefabrication [PDF]

open access: yes, 2008
The use of prefabrication in design exemplar houses has escalated in Australia in the past decade. The same level of design quality has not been applied to the design of prefabricated school buildings.
Newton, Clare
core   +1 more source

Design and Geographically Liberated Difference [PDF]

open access: yes, 2011
The concept of geographically liberated difference has emerged from the overlap of cultural studies and economics as a critique of the effects of globalisation on cultures through the manufacturing and distribution of artefacts with unique differences ...
Barker, Tom, Hall, Ashley
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Design and semantics of form and movement (DeSForM 2006) [PDF]

open access: yes, 2006
Design and Semantics of Form and Movement (DeSForM) grew from applied research exploring emerging design methods and practices to support new generation product and interface design.
Feijs, Loe   +2 more
core  

Control of virtual environments for young people with learning difficulties [PDF]

open access: yes, 2002
Purpose: The objective of this research is to identify the requirements for the selection or development of usable virtual environment (VE) interface devices for young people with learning disabilities.
Brown, D, Lannen, T, Powell, H
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

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