Results 91 to 100 of about 2,252,872 (309)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Comments on: Huang et al. (2019) Emerging trends and research foci in gastrointestinal microbiome’, J. Transl. Med., 17: 67

Journal of Translational Medicine, 2020
Yuh-Shan Ho
doaj   +1 more source

Partial Indexation, Trend Inflation, and the Hybrid Phillips Curve [PDF]

This paper proposes a full description of the Calvo price-setting model based on partial prices indexation and studies the interaction between partial indexation and trend inflation.
Sahuc, J-G.
core  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Trend Inflation, Wage Indexation, and Determinacy in the U.S. [PDF]

We combine an estimated monetary policy rule featuring time-varying trend inflation and stochastic coefficients with a medium scale New Keynesian framework calibrated on the U.S. economy.
Nicola Branzoli, Efrem Castelnuovo, Guido Ascari   +2 more
core  

Excess burden of constipation in Parkinson's disease: A pilot study

, 2006
An analysis was undertaken of clinic-based questionnaires that asked people with Parkinson's disease and a control group of older people without a known neurological condition about their experiences of constipation.
Kimber, A, Trend, P, Kaye, J, Gage, H, Kimber, Alan, Kaye, J., Gage, Heather, Trend, Patrick, Kimber, A., Gage, H., Storey, Lesley, Trend, P., Storey, L, Storey, L., Kaye, Julie   +14 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Future Research and Trends in Ultra-Wideband Indoor Tag Localization

IEEE Access
Ultra-wideband (UWB) signals are widely used for indoor tag localization because of their high accuracy, wide bandwidth, and low power consumption. The diversity and breadth of research in the field of UWB-indoor tag localization can be confusing for new
Gita Indah Hapsari, Rendy Munadi, Bayu Erfianto, Indrarini Dyah Irawati   +3 more
doaj   +1 more source

Spurious regression under broken trend stationarity [PDF]

We study the phenomenon of spurious regression between two random variables when the generating mechanism for individual series follows a stationary process around a trend with (possibly) multiple breaks in its level and slope.
Daniel Ventosa-Santaularia, Antonio E. Noriega   +1 more
core  

Historic ocean acidification of Loch Sween revealed by correlative geochemical imaging and high-resolution boron isotope analysis of Boreolithothamniom cf. soriferum

Ocean Acidification (OA) arises from the increase in atmospheric carbon dioxide concentration following the industrial revolution. The ecological and socio-economic consequences of OA were first identified around 10–15 years ago but remain poorly ...
MacDonald, Ellen, Standish, Christopher D., Kamenos, NA, Kamenos, Nicholas A., Trend, J, Trend, Jacob, Page, Tessa M., Standish, CD, Foster, Gavin L., MacDonald, E, Page, TM, Foster, GL   +11 more
core   +1 more source