Results 81 to 90 of about 5,617,166 (283)

Reaction-diffusion model for brain spacetime dynamics

open access: yesBiophysical Reports
The human brain exhibits intricate spatiotemporal dynamics, which can be described and understood through the framework of complex dynamic systems theory.
Qiang Li, Vince D. Calhoun
doaj   +1 more source

Effect of Radiation and Magnetohydrodynamic Free Convection Boundary Layer Flow on a Solid Sphere with Convective Boundary Conditions

open access: yesWalailak Journal of Science and Technology, 2014
In this paper, the effect of radiation on magnetohydrodynamic free convection boundary layer flow on a solid sphere with convective boundary conditions, in which the heat is supplied through a bounding surface of finite thickness and finite heat capacity,
Hamzeh Taha ALKASASBEH   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Decreased Cross-Domain Mutual Information in Schizophrenia From Dynamic Connectivity States

open access: yesFrontiers in Neuroscience, 2019
The study of dynamic functional network connectivity (dFNC) has been important to understand the healthy and diseased brain. Recent developments model groups of functionally related brain structures (defined as functional domains) as entities that can ...
Mustafa S. Salman   +5 more
doaj   +1 more source

Trends in economic research: An international perspective [PDF]

open access: yes
Given the recent efforts in several countries to reorganize the research institutional setting to improve research productivity, our analysis addresses the following questions: To which extent has the recent awareness over international quality standards
Ana Rute Cardoso   +2 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Adolescent brain maturation associated with environmental factors: a multivariate analysis

open access: yesFrontiers in Neuroimaging
Human adolescence marks a crucial phase of extensive brain development, highly susceptible to environmental influences. Employing brain age estimation to assess individual brain aging, we categorized individuals (N = 7,435, aged 9–10 years old) from the ...
Bhaskar Ray   +17 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Trends and Design Relating literature to industry practice [PDF]

open access: yes, 2008
In a crowded market place, where technology and functionality are not enough to differentiate a product from its competitors, the product’s appearance is a major driver of consumer preference.
Eckert, Claudia   +2 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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