Results 71 to 80 of about 726,944 (258)

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer

Advanced Science, EarlyView.
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu, Kangkang Liu, Keruo Wang, Heyang Guan, Jiaming Fan, Taipeng Li, Jiaru Hao, Zeyuan Wang, Yongchao Yan, Jiatong Chen, Yuan Ma, Yang Yang, Yuanjie Niu   +12 more
wiley   +1 more source

Hyperspectral imaging for resection margin assessment during cancer surgery [PDF]

, 2019
Purpose: Complete tumor removal during cancer surgery remains challenging due to the lack of accurate techniques for intraoperative margin assessment.
Kho, Esther, van Duijnhoven, Frederieke, Sterenborg, Henricus J.C.M., Ruers, Theo J. M., Van de Vijver, Koen, van de Vijver, Koen K., de Boer, Lisanne L., Ruers, Theo J.M., Sterenborg, Henricus J. C. M., Peeters, Marie Jeanne T.F.D.Vrancken, Peeters, Marie-Jeanne T. F. D. Vrancken, Vrancken Peeters, Marie-Jeanne T.F.D.   +11 more
core   +1 more source

Stapling cartridge lavage cytology in limited resection for pulmonary malignant tumors: assessment of cytological status of the surgical margin

Heliyon, 2019
Introduction: Sublobar resection in primary lung cancer and pulmonary metastatic tumor can result in recurrence at the surgical margin. Confirming the absence of tumor cells at the cut-end is important.
Tomohiro Miyoshi, Junji Yoshida, Keiju Aokage, Kenta Tane, Genichiro Ishii, Masahiro Tsuboi   +5 more
doaj   +1 more source

Performance Estimation and Ex Vivo Validation of Untethered Magnetic Robots in Soft Tissue

Advanced Science, EarlyView.
This study presents an empirical model that quantitatively predicts the step‐out frequency of screw‐type untethered magnetic robots (UMRs) in soft viscoelastic environments, including ex vivo brain tissue. By integrating key parameters into a dimensionless framework, the model enables estimation of robot performance across a range of biological ...
Leendert‐Jan W. Ligtenberg, Thijs J. van der Burg, Stijn Y. Kolkman, Santiago Saavedra Castano, David Fernandez Rivas, Anke Klingner, Roger M. L. M. Lomme, Lucas S. Joziasse, Dorothee Wasserberg, H. Remco Liefers, Doron Ben Ami, Udi Sadeh, Oded Shoseyov, Giulio Dagnino, Pascal Jonkheijm, Jurgen J. Fütterer, Stefano Stramigioli, J. Frank W. Nijsen, Michiel C. Warlé, Islam S. M. Khalil   +19 more
wiley   +1 more source

Locally Advanced Pancreatic Head Cancer: Margin-Positive Resection or Bypass?

, 2012
Pancreatic cancer is a highly aggressive disease with poor survival. The only effective therapy offering long-term survival is complete surgical resection.
Ulrich Friedrich Wellner, Sick, Olivia, Frank Makowiec, Jens Höppner, Wellner, Ulrich, Makowiec, Frank, Keck, Tobias, Bausch, Dirk, Dirk Bausch, Ulrich Theodor Hopt, Hopt, Ulrich T., Olivia Sick, Tobias Keck, Höppner, Jens   +13 more
core   +1 more source

Is a 3 mm Surgical Margin Safe for Basal Cell Carcinoma in the Head and Neck that is Less than 2 cm, Considering Different Risk Factors?

Archives of Plastic Surgery
Background Basal cell carcinoma (BCC) is the most common type of nonmelanoma skin cancer. Typically, resection requires a safety margin of ≥4 mm.
Min-Jun Yong, Seok-Ju Yoo, Hea-Kyeong Shin   +2 more
doaj   +1 more source

Resectable adenocarcinomas in the pancreatic head: the retroperitoneal resection margin is an independent prognostic factor

BMC Cancer, 2008
Background The retroperitoneal margin is frequently microscopically tumour positive in non-curative periampullary adenocarcinoma resections. This margin should be evaluated by serial perpendicular sectioning. The aim of the study was to determine whether
Eide Tor J, Cvancarova Milada, Farstad Inger N, Tafjord Svetlana, Westgaard Arne, Mathisen Oystein, Clausen Ole Petter F, Gladhaug Ivar P   +7 more
doaj   +1 more source

Modification‐Selective Inhibition of Succinate Dehydrogenase a Enables Tumor‐Restricted Mitochondrial Modulation

Advanced Science, EarlyView.
This work identifies acetylation‐dependent SDHA homeostasis as a determinant of tumor‐specific metabolic vulnerability. Guided by this mechanism, a modification‐selective inhibitor, ZPI‐3, selectively targets non‐acetylated SDHA, achieving tumor‐restricted SDH inhibition and effective bladder cancer control. Differential responses in clinical specimens
Kaikai Xu, Lulu Kong, Kebin Ye, Xinlu Bao, Haowen Liu, Ning Wang, Yongming Deng, Wei Wang, Shaohua Wei, Lin Zhou   +9 more
wiley   +1 more source

Carcinoma in situ at the bronchial resection margin: a review. [PDF]

, 2011
Carcinoma in situ at the mucosal bronchial resection margin is a rarely reported event. At present, such histological findings at the resection margins are classified as R1(is), thus representing an incomplete resection.
Travis, William D, Goldstraw, P, Travis, William D., International Association for the Study of Lung Cancer (IASLC) International Staging Committee, -, Van Meerbeeck, Jan, Rami-Porta, Ramón, Goldstraw, Peter, Peter Goldstraw, Vallieres, E., Van Houtte, Paul, Ramon Rami-Porta, Postmus, P., International Association for the Study of Lung Cancer (IASLC) International Staging Committee, William D. Travis, Eric Vallières, Vallières, Eric, Travis, W.D., Paul Van Houtte, Rami-Porta, R., Van Houtte, P.   +19 more
core   +1 more source