Results 51 to 60 of about 845,239 (199)

Proliferation of latently infected CD4+ T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics

Journal of Experimental Medicine, 2017
A latent reservoir for HIV-1 in resting CD4+ T lymphocytes precludes cure. Mechanisms underlying reservoir stability are unclear. Recent studies suggest an unexpected degree of infected cell proliferation in vivo.
Nina N. Hosmane, K. J. Kwon, Katherine M. Bruner, A. Capoferri, Subul A. Beg, Daniel I. S. Rosenbloom, B. Keele, Y. Ho, J. Siliciano, R. Siliciano   +9 more
semanticscholar   +1 more source

Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy

Advanced Functional Materials, EarlyView.
Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi, Elias Huber, Leonie Karr, Johnny Tong, Andreas Richard Bausch, Friedrich Christian Simmel, Karen Alim   +6 more
wiley   +1 more source

Crossover Effects of Transition‐Metal Ions on Lithium‐Metal Anode in Localized High Concentration Electrolytes

Advanced Functional Materials, EarlyView.
This study highlights the impact of transition‐metal (TM) ions (Ni2⁺, Mn2⁺, Co2⁺) on the performance of lithium‐metal anode in localized high‐concentration electrolytes. Mn2⁺ and Co2⁺ destabilize SEI and CEI layers, causing capacity fade and overpotential, while Ni2⁺ shows minimal effects. These findings underscore the need for electrolyte optimization
Zezhou Guo, Zehao Cui, Arumugam Manthiram   +2 more
wiley   +1 more source

Representation and improved parameterization of reservoir operation in hydrological and land-surface models

Hydrology and Earth System Sciences, 2019
. Reservoirs significantly affect flow regimes in watershed systems by changing the magnitude and timing of streamflows. Failure to represent these effects limits the performance of hydrological and land-surface models (H-LSMs) in the many highly ...
Fuad Yassin, S. Razavi, M. Elshamy, B. Davison, G. Sapriza-Azuri, H. Wheater   +5 more
semanticscholar   +1 more source

Evolving Platinum‐Copper Nanostructures for Enhanced Photothermal Therapy and Controlled Copper Release in Cancer Therapy

Advanced Functional Materials, EarlyView.
Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro, María Sancho‐Albero, Silvia Miguel, Andrea Mosseri, Felipe Hornos, Rafael Contreras‐Montoya, Jose L. Hueso, Jesus Santamaria   +7 more
wiley   +1 more source

Recent Advances in Physical Reservoir Computing: A Review [PDF]

Neural Networks, 2018
G. Tanaka, T. Yamane, J. Héroux, R. Nakane, Naoki Kanazawa, Seiji Takeda, H. Numata, D. Nakano, A. Hirose   +8 more
semanticscholar   +1 more source

Self‐supportive Three‐Way Photoelectrochemical System Achieving Uranium Recycling, Organic Oxidation, and Electricity Generation in Complex Waters

Advanced Functional Materials, EarlyView.
A self‐sustaining solar photoelectrochemical cell (SS‐PEC) is developed to recover uranium from aqueous UO22+ with concurrent organic oxidation and electricity production. The monolithical photoanode directly captures electrons from organic compounds, leading to the oxidation of organic compounds and the decomposition of uranium‐organic complexes ...
Yumei Wang, Qingming Zeng, Haodong Ji, Rongzhong Wang, Jiachen Wang, Yanjun Wen, Wonyong Choi, Qingyi Zeng   +7 more
wiley   +1 more source

Nanodiamond‐Infused Microgels for pH‐Tunable Rheology, Lubrication, and UV Protection

Advanced Functional Materials, EarlyView.
Microgels consisting of swollen polyacrylic acid polymer networks, impregnated with nanodiamonds provide protection from ultraviolet (UV) radiation harmful to human health. Nanodiamonds enable UV blockage and control of the rheology (flow) and lubrication (skin‐feel) of these microgel‐skincare‐mimics.
Pallav K. Jani, Sarvesh A. Nadkarni, Katherine J. Ernst, Barbara V. Farias, Chloe G. Hincher, Oluwatobi A. Ojuade, Yug C. Saraswat, Prottasha Sarker, Donald O. Freytes, Lilian C. Hsiao, Saad A. Khan   +10 more
wiley   +1 more source

Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART

Nature Communications, 2019
The HIV-1 reservoir is the major hurdle to a cure. We here evaluate viral and host characteristics associated with reservoir size and long-term dynamics in 1,057 individuals on suppressive antiretroviral therapy for a median of 5.4 years.
N. Bachmann, Chantal von Siebenthal, Valentina Vongrad, Teja Turk, Kathrin Neumann, N. Beerenwinkel, Jasmina Bogojeska, J. Fellay, Volker Roth, Yik Lim Kok, Christian W. Thorball, A. Borghesi, S. Parbhoo, Mario Wieser, J. Böni, M. Perreau, T. Klimkait, S. Yerly, M. Battegay, A. Rauch, M. Hoffmann, E. Bernasconi, M. Cavassini, R. Kouyos, H. Günthard, K. Metzner   +25 more
semanticscholar   +1 more source

Selective Membrane for Non‐Aqueous Electrochemical Flow Cells

Advanced Functional Materials, EarlyView.
Sulfonated fixed charge functionalization is increased to improve the conductivity of a cation exchange membrane in a non‐aqueous electrochemical cell. Based on ex situ analyses, the material achieved the highest selectivity for this type of system to date.
Charles R. Leroux, Geoffrey M. Geise, Gary M. Koenig Jr   +2 more
wiley   +1 more source