Results 51 to 60 of about 6,059,826 (263)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Navigation in GNSS-Denied Environment Based on Observation of RSOs and Stars

Guidance, Navigation and Control
Navigating in an environment, where Global Navigation Satellite System (GNSS) signals are unavailable, presents a formidable challenge. A feasible strategy involves integrating stellar observations with inertial information to realize precise navigation.
Jiayu Wang, Weiping Yang, Guoliang Yang, Yu Tian, Xiaokun Ding   +4 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Performance and Detectability Analysis of Resident Space Objects Using an S-Band Bi-Static Radar with the Sardinia Radio Telescope as Receiver

Remote Sensing
The continuous growth of the population of Resident Space Objects (RSOs) poses increasing challenges for Space Situational Awareness (SSA), particularly in terms of detection capability and collision risk mitigation.
Luca Schirru
doaj   +1 more source

Dealing with nonlinearities in orbit determination of resident space objects

, 2020
Space activities are continuously at risk due to the ever-increasing amount of uncontrolled space objects, called space debris, which can collide with operational spacecraft. Therefore, space agencies have started space situational awareness (SSA) programs, which aim to provide timely and accurate data regarding the space environment and hazards to ...
openaire   +3 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

On-Orbit Resident Space Object (RSO) Detection Using Commercial Grade Star Trackers [PDF]

, 2019
The resident space object (RSO) population, including both functioning satellites and on-orbit debris, has grown to the point where dedicated ground and space-based networks are needed to maintain up-to-date catalogues of their orbits.
Clemens, Samuel David
core  

Characterizing Satellite Geometry via Accelerated 3D Gaussian Splatting

Aerospace
The accelerating deployment of spacecraft in orbit has generated interest in on-orbit servicing (OOS), inspection of spacecraft, and active debris removal (ADR).
Van Minh Nguyen, Emma Sandidge, Trupti Mahendrakar, Ryan T. White   +3 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source