Results 41 to 50 of about 11,631 (236)

Space Situational Awareness in Very Low Earth Orbit for Re-Entry Object Monitoring

Aerospace
As the number of objects in orbit increases every year, the number of objects re-entering Earth’s atmosphere grows as well. Re-entry path prediction is tricky, as atmospheric modeling lacks accuracy and requires constant monitoring of the object during ...
Ruth Huang, Regina S. K. Lee, Marianna Veltri, Vithurshan Suthakar, Angel Porras-Hermoso   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Light-Curve Classification of Resident Space Objects for Space Situational Awareness: A Scoping Review

Aerospace
The proliferation of Resident Space Objects (RSOs), including satellites, rocket bodies, and debris, poses escalating challenges for Space Situational Awareness (SSA). Optical light curves capture temporal brightness variations influenced by factors such
Minyoung Hwang, Vithurshan Suthakar, Randa Qashoa, Regina S. K. Lee, Gunho Sohn   +4 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Navigation in GNSS-Denied Environment Based on Observation of RSOs and Stars

Guidance, Navigation and Control
Navigating in an environment, where Global Navigation Satellite System (GNSS) signals are unavailable, presents a formidable challenge. A feasible strategy involves integrating stellar observations with inertial information to realize precise navigation.
Jiayu Wang, Weiping Yang, Guoliang Yang, Yu Tian, Xiaokun Ding   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Performance and Detectability Analysis of Resident Space Objects Using an S-Band Bi-Static Radar with the Sardinia Radio Telescope as Receiver

Remote Sensing
The continuous growth of the population of Resident Space Objects (RSOs) poses increasing challenges for Space Situational Awareness (SSA), particularly in terms of detection capability and collision risk mitigation.
Luca Schirru
doaj   +1 more source

Dealing with nonlinearities in orbit determination of resident space objects

, 2020
Space activities are continuously at risk due to the ever-increasing amount of uncontrolled space objects, called space debris, which can collide with operational spacecraft. Therefore, space agencies have started space situational awareness (SSA) programs, which aim to provide timely and accurate data regarding the space environment and hazards to ...
openaire   +3 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source