Results 41 to 50 of about 6,059,826 (263)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Feature Detection of Non-Cooperative and Rotating Space Objects through Bayesian Optimization

Sensors
In this paper, we propose a Bayesian Optimization (BO)-based strategy using the Gaussian Process (GP) for feature detection of a known but non-cooperative space object by a chaser with a monocular camera and a single-beam LIDAR in a close-proximity ...
Rabiul Hasan Kabir, Xiaoli Bai
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Photometric Characterization of Space Objects: From Classical BRDF Models to Data-Driven Prediction

Aerospace
The rapid proliferation of resident space objects has made space situational awareness critically dependent on accurate characterization of non-cooperative targets using photometric light curves.
Liu Yang, Can Xu, Yasheng Zhang
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Technology Demonstration of Space Situational Awareness (SSA) Mission on Stratospheric Balloon Platform

Remote Sensing
As the number of resident space objects (RSOs) orbiting Earth increases, the risk of collision increases, and mitigating this risk requires the detection, identification, characterization, and tracking of as many RSOs as possible in view at any given ...
Randa Qashoa, Vithurshan Suthakar, Gabriel Chianelli, Perushan Kunalakantha, Regina S. K. Lee   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Space Situational Awareness in Very Low Earth Orbit for Re-Entry Object Monitoring

Aerospace
As the number of objects in orbit increases every year, the number of objects re-entering Earth’s atmosphere grows as well. Re-entry path prediction is tricky, as atmospheric modeling lacks accuracy and requires constant monitoring of the object during ...
Ruth Huang, Regina S. K. Lee, Marianna Veltri, Vithurshan Suthakar, Angel Porras-Hermoso   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

On-line learning of shape information for object segmentation and tracking [PDF]

, 2009
We present segmentation and tracking of deformable objects using non-linear on-line learning of high-level shape information in the form of a level set function.
Chiverton, John, John, Chiverton, John Chiverton, Xianghua Xie, Xie, Xianghua, Majid Mirmehdi, Mirmehdi, Majid, Xianghua, Xie   +7 more
core   +1 more source