Results 31 to 40 of about 11,631 (236)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Dynamic Scene 3D Reconstruction of an Uncooperative Resident Space Object
AIAA SCITECH 2026 ForumCharacterization of uncooperative Resident Space Objects (RSO) play a crucial role in On-Orbit Servicing (OOS) and Active Debris Removal (ADR) missions to assess the geometry and motion properties. To address the challenges of reconstructing tumbling uncooperative targets, this study evaluates the performance of existing state-of-the-art 3D ...
Bala Prenith Reddy Gopu +7 more
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Instance Segmentation for Feature Recognition on Noncooperative Resident Space Objects
Journal of Spacecraft and Rockets, 2022 Active debris removal and unmanned on-orbit servicing missions have gained interest in the last few years, along with the possibility to perform them through the use of an autonomous chasing spacecraft. In this work, new resources are proposed to aid the implementation of guidance, navigation, and control algorithms for satellites devoted to the ...
Niccolò Faraco +2 more
openaire +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Photometric Characterization of Space Objects: From Classical BRDF Models to Data-Driven Prediction
AerospaceThe rapid proliferation of resident space objects has made space situational awareness critically dependent on accurate characterization of non-cooperative targets using photometric light curves.
Liu Yang, Can Xu, Yasheng Zhang
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Remote SensingAs the number of resident space objects (RSOs) orbiting Earth increases, the risk of collision increases, and mitigating this risk requires the detection, identification, characterization, and tracking of as many RSOs as possible in view at any given ...
Randa Qashoa +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source