Results 61 to 70 of about 390,638 (295)

Evaluation of residual stresses in CO2 laser beam welding of SS316L weldments using FEA

open access: yesMaterials Research Express, 2023
Laser welding is used in critical component production when tight tolerances like minimal distortions and residual stresses are required. Laser beam welding offers a lower heat input, a smaller heat affected zone, lower residual stresses, minimum ...
Harinadh Vemanaboina   +9 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Observer-based Fault Detection and Diagnosis for Mechanical Transmission Systems with Sensorless Variable Speed Drives [PDF]

open access: yes, 2015
Observer based approaches are commonly embedded in sensorless variable speed drives for the purpose of speed control. It estimates system variables to produce errors or residual signals in conjunction with corresponding measurements. The residual signals
Abusaad, Samieh   +3 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Mitigating the Inrush Current of V/V Transformers Using Railway Conditioners

open access: yesIEEE Access
Inrush current is high-magnitude current drawn by power transformers upon energization. The severity of inrush current depends on factors such as the transformer’s residual flux and the voltage phase angle at the energization instant.
Amir Aghazadeh   +3 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Mixed-layer Heat Budget in W er Heat Budget in Western and Eastern T estern and Eastern Tropical P opical Pacific Ocean during El Niño Event in 2015/2016

open access: yesMakara Journal of Science, 2020
Temporal variation of mixed-layer heat budget at two contrasting locations, namely, western Pacific (warm water pool) and eastern Pacific (cold tongue) during the extreme El Niño phenomenon in 2015/2016 is evaluated.
Willy Anta Kusuma   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Solar Meridional Flow in the Shallow Interior during the Rising Phase of Cycle 24

open access: yes, 2014
Solar subsurface zonal and meridional-flow profiles during the rising phase of solar cycle 24 are studied using time-distance helioseismology technique.
Bogart, R. S.   +2 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

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