Results 111 to 120 of about 125,543 (299)

Residual log-periodogram inference for long-run relationships. [PDF]

We assume that some consistent estimator of an equilibrium relation between non-stationary series integrated of order d(0.5,1.5) is used to compute residuals (or differences thereof).
Marmol, Francesc, Velasco, Carlos, Hassler, U.   +2 more
core   +2 more sources

Bounded sine hyperbolic distribution with applications to real datasets

Kuwait Journal of Science
In this paper, a novel hyperbolic trigonometric probability distribution with a bounded support on (0,1) named the bounded sine hyperbolic (BSH) distribution is proposed. It has a simple closed form cumulative distribution function (CDF).
Anwaar Saeed, Abdus Saboor, Farrukh Jamal, Najwan Alsadat, Oluwafemi Samson Balogun, Abdoulie Faal, Mohammed Elgarhy   +6 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Binomial Poisson Ailamujia model with statistical properties and application

Journal of Radiation Research and Applied Sciences
In this study, an improved extension of the Poisson-Ailamujia distribution is introduced. The new distribution was derived using a binomial mixing approach, and the new model is named the “Binomial Poisson-Ailamujia (Bin-PA)” distribution. Some important
Safar M. Alghamdi, Muhammad Ahsan-ul-Haq, Olayan Albalawi, Majdah Mohammed Badr, Eslam Hussam, H.E. Semary, M.A. Abdelkawy   +6 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Maximum likelihood fitting using ordinary least squares algorithms

, 2002
In this paper a general algorithm is provided for maximum likelihood fitting of deterministic models subject to Gaussian-distributed residual variation (including any type of non-singular covariance).
Sidiropoulos, N.D., Smilde, A. K., Nicholaos D. Sidiropoulos, Sidiropoulos, N. D., Smilde, A.K., Bro, R., Rasmus Bro, Age K. Smilde, Smilde, A.K.; id_orcid   +8 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Does the Solow Residual for Korea Reflect Pure Technology Shocks? [PDF]

This study investigates the relationship between the measured Solow residual and demand side variables for the Korean economy. The measured Solow residuals are shown to be Granger-caused by some demand side variables such as exports, M1, and government ...
Hyunjoon Lim, Sangho Kim
core  

A New Hybrid Class of Distributions: Model Characteristics and Stress–Strength Reliability Studies

Axioms
This study proposes a generalized family of distributions to enhance flexibility in modeling complex engineering and biomedical data. The framework unifies existing models and improves reliability analysis in both engineering and biomedical applications ...
Mustapha Muhammad, Jinsen Xiao, Badamasi Abba, Isyaku Muhammad, Refka Ghodhbani   +4 more
doaj   +1 more source