Results 51 to 60 of about 125,543 (299)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A New Three-Parameter Flexible Unit Distribution and Its Quantile Regression Model

open access: yesIEEE Access
This paper introduces a novel Poisson-unit-Weibull (PUW) distribution, which is defined on a unit domain and characterized by three parameters. The PUW distribution is capable of accommodating diverse non-monotone failure rates.
Mustapha Muhammad   +5 more
doaj   +1 more source

New Partially Linear Regression and Machine Learning Models Applied to Agronomic Data

open access: yesAxioms, 2023
Regression analysis can be appropriate to describe a nonlinear relationship between the response variable and the explanatory variables. This article describes the construction of a partially linear regression model with two systematic components based ...
Gabriela M. Rodrigues   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Empirical likelihood inference for the Rao-Hartley-Cochran sampling design

open access: yes, 2016
The Hartley-Rao-Cochran sampling design is an unequal probability sampling design which can be used to select samples from finite populations. We propose to adjust the empirical likelihood approach for the Hartley-Rao-Cochran sampling design.
Yves G. Berger, Berger, Yves G.
core   +1 more source

A modified power-law model: Properties, estimation, and applications

open access: yesOpen Physics, 2023
Models of various physical, biological, and artificial phenomena follow a power law over multiple magnitudes. This article presents a modified Pareto model with an upside-down shape and an adjustable right tail. The moments, quantiles, failure rate, mean
Shrahili Mansour, Kayid Mohamed
doaj   +1 more source

Model-Robust Estimation of Multiple-Group Structural Equation Models

open access: yesAlgorithms, 2023
Structural equation models (SEM) are widely used in the social sciences. They model the relationships between latent variables in structural models, while defining the latent variables by observed variables in measurement models.
Alexander Robitzsch
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Some Results on a Generalized Residual Entropy based on Order Statistics

open access: yesStatistica, 2014
In the present paper, we discuss some monotone properties of the GRE of order (α, β) in order statistics under various assumptions. It is shown that monotone properties are preserved under the formation of a parallel system but not under the formation of
Suchandan Kayal
doaj   +1 more source

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