Results 71 to 80 of about 1,093,011 (314)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Determination of load sequence effects on the degradation and failure of composite materials [PDF]
A theoretical model was established to predict the fatigue behavior of composite materials, with emphasis placed on predictions of the degradation of residual strength and residual stiffness during fatigue cycling.
Jones, D. L., Yang, J. N.
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The fatigue behavior of materials for the supersonic transport [PDF]
Crack propagation behavior, residual static strength, and base fatigue strength of supersonic transport skin ...
Healy, M. S. +3 more
core +1 more source
Effect of distortion on the buckling strength of stiffened panels [PDF]
, 2009 This paper predicts the behaviour of stiffened plates with different distortion levels in order to address a rational structural design procedure as pre-existing and fabricationrelated (like weld-induced) initial geometrical distortion is of great ...
Chaithanya, Pretheesh Paul +3 more
core +2 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Development of Stress Relief Treatments for High Strength Aluminum Alloys Annual Report No. 2, 13 Aug. 1964 - 13 Aug. 1965 [PDF]
Residual stress, strength, and toughness response of high strength aluminum alloys subjected to time-temperature ...
Kulin, S. A., Orner, G. M.
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Calculation of sub-surface-initiated fatigue fractures in gears [PDF]
, 2019 Power-transmitting gears are typically heat-treated, most often case-hardened, to improve the fatigue strength and therefore to ensure higher fatigue life.
Müller, Daniel +2 more
core
Spin-Isospin Excitations and Muon Capture by Nuclei
, 2005 By analyzing the energy-weighted moments of the strength function calculated in RPA and beyond it is shown that the explanation of the effect of missing strength of Gamow-Teller transitions requires that residual interaction produce high-excited $1 ...
Livius Trache +3 more
core +1 more source