Results 91 to 100 of about 348,093 (266)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Determination of Residual Stress Distributions in Autofrettaged Thick Cylinders [PDF]

open access: yes, 2008
High pressure vessels such as gun barrels are autofrettaged in order to increase their operating pressure and fatigue life. Autofrettage causes plastic expansion of the inner section of the cylinder – setting up residual compressive stresses at the ...
Gibson, Michael C.
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Residual stresses in bulk ceramics

open access: yes, 2022
S.274-285Residual stresses in ceramics are of interest for two reasons. First, residual stresses are superimposed on external stresses and thus influence the service behavior of the machined parts.
Pfeiffer, W.
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Measurement and modelling of the transient thermal-mechanical strain field during GMA welding [PDF]

open access: yes, 2011
The state of residual stress in welded joints is a well-studied topic, and many methodsof residual stress measurement are now available. However, far less is known aboutthe transient strains which occur during the welding process, even though these ...
Colegrove, Paul A.   +3 more
core  

Interfacial strength in thermoplastic composites - at last an industry friendly measurement method?

open access: yes, 2001
Many elegant techniques have been developed for the quantification of composite micro-mechanical parameters in recent years. Unfortunately, most of these techniques have found little enthusiastic support in the industrial product development environment,
Thomason, J.L.
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Residual stresses in high strength steel welded box sections

open access: yes, 2016
Induced residual tensile and compressive stresses generated by the fabrication process can cause premature buckling and reduce the ultimate axial strength of welded steel box sections subjected to compressive loads.
Paradowska, Anna   +4 more
core   +1 more source

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