Results 81 to 90 of about 348,093 (266)

Effective residual shear strength and total residual strength under different dry density and shear rate conditions.

open access: yes, 2022
Effective residual shear strength and total residual strength under different dry density and shear rate conditions.
Jiangbo Xu (12245677)   +10 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

The role of residual thermal stress in interfacial strength of polymer composites by a novel single fibre technique

open access: yes, 2012
The temperature dependence of the interfacial properties of glass fibre reinforced polypropylene and epoxy composites was investigated using a novel microbond test in the temperature controlled environment of a thermo-mechanical analyser.
Thomason, James, Yang, Liu
core  

The Shear Strength of Granular Materials with Dispersed and Non-Dispersed Oversized Particles [PDF]

open access: yes, 2013
Soils containing dispersed and non-dispersed large particles (greater than # 4 sieve) form part of many engineered fills, glacial tills, debris flows, and residual soil deposits.
Seminsky, Leanna
core  

Residual circulation trajectories and transit times into the extratropical lowermost stratosphere [PDF]

open access: yes, 2010
Transport into the extratropical lowermost stratosphere (LMS) can be divided into a slow part (time-scale of several months to years) associated with the global-scale stratospheric residual circulation and a fast part (time-scale of days to a few months)
Bönisch, Harald   +3 more
core   +1 more source

Welding residual stresses depending on solid-state transformation behaviour studied by numerical and experimental methods

open access: yes, 2022
S.85-90The development of high-strength structural steels with yield strengths up to 1000 MPa results in the requirement of suitable filler materials for welding.
Kannengiesser, T.   +4 more
core   +1 more source

Explainable Ensemble Learning Model for Residual Strength Forecasting of Defective Pipelines

open access: yesApplied Sciences
The accurate prediction of the residual strength of defective pipelines is a critical prerequisite for ensuring the safe operation of oil and gas pipelines, and it holds significant implications for the pipeline’s remaining service life and preventive ...
Hongbo Liu, Xiangzhao Meng
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Prediction Method of Residual Strength of Casing with Different Corrosion Defects

open access: yesShiyou jixie, 2019
To predict the residual strength of the corroded casing in production wells, based on the regularized characterization of the shape of the corrosion pit on the casing surface, a mechanical analysis model of casing that can simulate the corrosion pits ...
Xu Guoxian   +3 more
doaj  

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