Results 91 to 100 of about 5,765,787 (386)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Process Optimization Simulation of Residual Stress in Martensitic Steel Considering Phase Transformation

open access: yesCrystals
The solid phase transformation of martensitic steel during heat treatment will affect the stress and temperature. Previous residual stress prediction models ignore the effect of phase transition on residual stress.
Yuzheng Cui, Guang Yang
doaj   +1 more source

Stress Monitoring of Post-processed MEMS Silicon Microbridge Structures Using Raman Spectroscopy [PDF]

open access: yes, 2012
Inherent residual stresses during material deposition can have profound effects on the functionality and reliability of fabricated Micro-Electro-Mechanical Systems (MEMS) devices.
Coutu, Ronald A., Jr.   +1 more
core   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Residual Stresses in Machining of AISI 52100 Steel under Dry and Cryogenic Conditions: A Brief Summary [PDF]

open access: yes, 2014
17th Conference on Material Forming (ESAFORM) - FinlandResidual stress is one of the most important surface integrity parameter that can significantly affect the service performance of a mechanical component, such as: contact fatigue, corrosion ...
BATISTA, Antonio   +3 more
core   +4 more sources

Processing Parameter Effects on Residual Stress and Mechanical Properties of Selective Laser Melted Ti6Al4V

open access: yesJournal of materials engineering and performance (Print), 2018
Selective laser melting (SLM) process is characterized by large temperature gradients resulting in high levels of residual stress within the additively manufactured metallic structure.
H. Ali, H. Ghadbeigi, K. Mumtaz
semanticscholar   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Simulation of vessel tissue remodeling with residual stress: an application to in-stent restenosis

open access: yesInternational Journal of Smart and Nano Materials, 2019
We present a numerical procedure to model the artery wall remodeling stimulated by stenting considering varying degree of residual stresses. This framework sets up biological remodeling with the existence of residual stress. Previous studies suggest that
Jie Cheng, Lucy T. Zhang
doaj   +1 more source

Evaluation of residual stress relaxation and its effect on fatigue strength of AISI 316L stainless steel ground surfaces: Experimental and numerical approaches [PDF]

open access: yes, 2013
This paper is aimed at evaluating the residual stress relaxation and its effect on the fatigue strength of AISI 316L steel ground surfaces in comparison to electro-polished surfaces.
BRAHAM, Chedly   +2 more
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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