Results 101 to 110 of about 5,765,787 (386)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The effect of vibratory stress on the welding microstructure and residual stress distribution [PDF]

open access: yes, 2001
Previous studies have suggested that weld microstructure may be modified by the presence of static stresses. In this investigation, vibratory stress was applied to mild steel specimens while they were being welded to observe its effect on the residual ...
Munsi, A.S.M.Y.   +2 more
core  

Residual stress relaxation and microstructure in ZnO thin films [PDF]

open access: yes, 2006
Stability under normal environmental conditions over a long period of time is crucial for sustainable thin-film device performance. Pure ZnO films with thicknesses in the 140 - 450 nm range were deposited on amorphous glass microscope slides and (100 ...
Gulgun, Mehmet Ali   +3 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Concentric tubes cold-bonded by drawing and internal expansion [PDF]

open access: yes, 1971
Metal tubes bonded together without heat application or brazing materials retain strength at elevated temperatures, and when subjected to constant or cyclic temperature gradients.
Hymes, L. C., Stone, C. C.
core   +1 more source

Tomography of small residual stresses

open access: yes, 2012
In this paper we study the inverse problem of determining the residual stress in Man's model using tomographic data. Theoretically, the tomographic data is obtained at zero approximation of geometrical optics for Man's residual stress model.
Sharafutdinov, Vladimir, Wang, Jenn-Nan
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy