INFLUENCE OF THE STIFFNESS AND FRICTIONAL CHARACTERISTICS ON THE SHANK TORQUE OF SCREWS IN BOLTED JOINTS [PDF]
, 2018 This work aims at determining the influence of tribological and stiffness characteristics of a bolted joint on the residual shank torque of the screw.
Cavalli, Omar +6 more
core
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Residual Stresses in Modelling Fatigue Lifetime of Gas Nitrided Iron-Based Alloys [PDF]
, 2016 G. Beck +4 more
openalex +1 more source
Modeling and Calculating of Residual Stress and Strain of Butt Welded Joint [PDF]
, 2021 Mô Phỏng
openalex +1 more source
Plastic dislocation and incompatibility density as indicators for residual stresses [PDF]
, 2019 Residual stresses in forming simulations are typically investigated by analyzing the remaining stress state after removing all external loadings. However, the generation of the stress state during forming remains unknown.
Landkammer, Philipp, Steinmann, Paul
core
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Pre-Deformation Induced Precipitation of Alloy Carbides and its Effect on Residual Stress
, 2023 Quhao Chen +8 more
openalex +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Parametric Analysis Using the Finite Element Method to Investigate Prosthetic Interface Stresses for Persons with Trans-tibial Amputation [PDF]
, 1996 A finite element (FE) model of the below-knee residual limb and prosthetic socket was created to investigate the effects of parameter variations on the interface stress distribution during static stance. This model was based upon geometric approximations
Childress, Dudley S. +1 more
core +1 more source