Biophysical evidence for intrinsic disorder in the C-terminal tails of the epidermal growth factor receptor (EGFR) and HER3 receptor tyrosine kinases [PDF]
, 2016 The epidermal growth factor receptor (EGFR)/ErbB family of receptor tyrosine kinases includes oncogenes important in the progression of breast and other cancers, and they are targets for many drug development strategies.
Bose, Ron +5 more
core +2 more sources
Crystal structure of a pre-chemistry viral RNA-dependent RNA polymerase suggests participation of two basic residues in catalysis [PDF]
, 2022 Rui Li, Meihua Wang, Peng Gong
openalex +1 more source
FEBS Letters, EarlyView.Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley +1 more source
Generation of Molecular Complexity from Cyclooctatetraene: Preparation of Optically Active Protected Aminocycloheptitols and Bicyclo[4.4.1]undecatriene [PDF]
, 1999 The racemic (6-cyclo-heptadienyl)Fe(CO)3+ cation ((±)-7), prepared from cyclooctatetraene, was treated with a variety of carbon and heteroatom nucleophiles.
El-Mansy, Mohamed F. +3 more
core +1 more source
Enhanced weathering of kimberlite residues in soils: Effects on CO2 fluxes and drainage chemistry [PDF]
, 2023 Zivi Schaffer +3 more
openalex +1 more source
International Journal of Pharmaceutics: X, 2019 Targeted delivery of therapeutics is an attractive strategy for vascular diseases. Recently, variable domains of heavy-chain-only antibodies (VHHs) have gained momentum as targeting ligands to achieve this.
Marc V.A. van Moorsel +8 more
doaj +1 more source
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source
Study on organic substrate production by composting swine manure
浙江大学学报. 农业与生命科学版, 2005 Wood shavings, tea and herb residue are mixed with different mass percent of swine manure, namely 0, 20%, 30% and 40%, as contrasting groups of the composting experiment for production of organic substrates.
WANG Kai-ying, ZHANG Yun, ZHU Xiao-lian
doaj +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
Hydrocracking of atmospheric distillable residue of Mongolian oil
Mongolian Journal of Chemistry, 2014 Many catalytic processes to refine heavy part of crude oil have attracted much interest due to declining reserves of light crude oils. This study focused on hydrocracking process of atmospheric distillable residue of Mongolian crude oil in the first time
Ts Tugsuu +3 more
doaj +1 more source