Results 41 to 50 of about 1,372,061 (319)

Preparation, characterization and pharmacokinetics of cyadox nanosuspension

Scientific Reports, 2017
An increase in number of newly developed synthetic drugs displays bioavailability constraints because of poor water solubility. Nanosuspensions formulation may help to overwhelm these problems by increasing dissolution velocity and saturation solubility.
Adeel Sattar, Dongmei Chen, Lishun Jiang, Yuanhu Pan, Yanfei Tao, Lingli Huang, Zhenli Liu, Shuyu Xie, Zonghui Yuan   +8 more
doaj   +1 more source

Study on the Metabolic Transformation Rule of Enrofloxacin Combined with Tilmicosin in Laying Hens

Metabolites, 2023
There is often abuse of drugs in livestock and poultry production, and the improper use of drugs leads to the existence of a low level of residues in eggs, which is a potential threat to human safety.
Jingchao Guo, Liyun Zhang, Yongxia Zhao, Awais Ihsan, Xu Wang, Yanfei Tao   +5 more
doaj   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

Analysis of the stability and affinity of BlaR-CTD protein to β-lactam antibiotics based on docking and mutagenesis studies

Journal of Biological Engineering, 2019
Owing to the thermal instability and low affinity of BlaR-CTD to some β-lactams, the receptor assay based on BlaR-CTD is limited in the detection of abundant variety of drugs and the result is often unstable.
Jianan Ning, Saeed Ahmed, Guyue Cheng, Ting Chen, Yulian Wang, Dapeng Peng, Zonghui Yuan   +6 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Determination of Susceptibility Breakpoint for Cefquinome against Streptococcus suis in Pigs

Antibiotics, 2021
Streptococcus suis (S. suis), a zoonotic pathogen, causes severe diseases in both pigs and human beings. Cefquinome can display excellent antibacterial activity against gram-negative and gram-positive bacteria.
Kun Mi, Mei Li, Lei Sun, Yixuan Hou, Kaixiang Zhou, Haihong Hao, Yuanhu Pan, Zhenli Liu, Changqing Xie, Lingli Huang   +9 more
doaj   +1 more source

Protein-bound veterinary drug residues in food [PDF]

, 1999
End of Project ReportBound residues of veterinary drugs have been recognised as an important aspect of food safety particularly (a) where such residues may persist for long periods after withdrawal of the drug treatment and (b) where the bound residues ...
Cadogan, Aodhmar, Coyle, Tiernan, O'Keeffe, Michael, Horne, Elizabeth   +3 more
core  

Chemical composition of ambient aerosol, ice residues and cloud droplet residues in mixed-phase clouds: single particle analysis during the Cloud and Aerosol Characterization Experiment (CLACE 6) [PDF]

, 2009
Two different single particle mass spectrometers were operated in parallel at the Swiss High Alpine Research Station Jungfraujoch (JFJ, 3580 m a.s.l.) during the Cloud and Aerosol Characterization Experiment (CLACE 6) in February and March 2007.
Cziczo, Daniel J., Curtius, Joachim, F. Drewnick, Cziczo, D.J., Klimach, Thomas, S. Borrmann, Kamphus, M., D. J. Cziczo, Keller, Livia, M. Kamphus, Drewnick, Frank, Mertes, Stephan, Borrmann, Stephan, Curtius, J., Ettner-Mahl, Matthias, Keller, L., Mertes, S., J. Curtius, Ettner-Mahl, M., Klimach, T., Borrmann, S., Kamphus, Michael, L. Keller, M. Ettner-Mahl, Drewnick, F., S. Mertes, T. Klimach   +26 more
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

The Prefrattini Residual [PDF]

Proceedings of the American Mathematical Society, 1976
The structure of a prefrattini subgroup in a finite solvable group is related to the structure of the prefrattini residual, that is, the residual for the formation of solvable n C
openaire   +1 more source