Results 51 to 60 of about 1,091,714 (269)
Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine +17 more
wiley +1 more source
Pharmaceutics, 2022 Antimicrobial resistance is a major public health issue. The pharmacokinetic/pharmacodynamic (PK/PD) model is an essential tool to optimize dosage regimens and alleviate the emergence of resistance.
Kun Mi +8 more
doaj +1 more source
Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
Pediatric Blood &Cancer, EarlyView.ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source
Metal‒organic frameworks for on-demand drug release and precision drug delivery
One Health AdvancesMetal‒organic frameworks (MOFs) are porous materials that combine high stability, large surface areas, excellent porosity, and low toxicity. The rapid development of these drugs has opened new opportunities to enhance drug efficacy with reduced adverse ...
Danlei Hu +6 more
doaj +1 more source
Current advances in immunoassays for the detection of antibiotics residues: a review
Food and Agricultural Immunology, 2020 Food contamination with antibiotic residues has become a worldwide problem due to the heavy and improper use of antibiotics. The development of fast, high-throughput, easy, and economical screening methods for the detection of antibiotic residues is an ...
Saeed Ahmed +9 more
doaj +1 more source
The Application of Hollow Fiber Cartridge in Biomedicine
Pharmaceutics, 2022 The hollow fiber cartridge has the advantages of good semi-permeability, high surface area to volume ratio, convenient operation, and so on. Its application in chemical analysis, drug in vitro experiment, hemodialysis, and other fields has been deeply ...
Yixuan Hou +7 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani +7 more
wiley +1 more source
Animal DiseasesThrough structure-based virtual screening, this study identified the botanical compound fangchinoline (FAN) as an inhibitor of the porcine aminopeptidase N (pAPN) receptor and evaluated its anti-transmissible gastroenteritis virus (TGEV) activity ...
Siyi Hu +9 more
doaj +1 more source
Evaluation of residue–residue contact prediction in CASP10 [PDF]
Proteins: Structure, Function, and Bioinformatics, 2013 ABSTRACTWe present the results of the assessment of the intramolecular residue‐residue contact predictions from 26 prediction groups participating in the 10th round of the CASP experiment. The most recently developed direct coupling analysis methods did not take part in the experiment likely because they require a very deep sequence alignment not ...
B. Monastyrskyy +4 more
openaire +3 more sources