Results 51 to 60 of about 264,697 (282)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Determination of parameters and kinetic evaluation for chromium (VI) removal using four resins
Eclética QuímicaThis research aimed to identify optimal studied variables for chromium (VI) removal using four resins (IRA 96, IRA 400, DOWEX 1x8, and LEWATIT). A 1,5-diphenylcarbazide method was used for the quantification of chromium (VI).
Stamber Alvaro Ramírez-Revilla +2 more
doaj +1 more source
Role of provisional restorations in endodontic therapy
Journal of Pharmacy and Bioallied Sciences, 2013 Root-canal treatment can be carried out in single visit in vital, non-infected teeth, eliminating the need for dressing and provisionalization. Many clinical cases with infected canals require dressing with antibacterial medicaments in a multivisit ...
Jambai Sampathkumar Sivakumar +2 more
doaj +1 more source
, 1995 Wet strength is defined as a paper which has extraordinary resistance to rupture or disintegration when saturated with water. This definition has been interpreted as if a paper sample retains more than 15% of its dry strength when wetted, it can be ...
Meyers, Todd
core +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Ageing of resin from Pinus species assessed by infrared spectroscopy [PDF]
, 2016 Resins obtained from Pinus genus species have been widely used in very different fields throughout history. As soon as the resins are secreted, molecular changes start altering their chemical, mechanical and optical properties.
Beltran Sanchidrian, Victòria +3 more
core +2 more sources
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
One-step volumetric additive manufacturing of complex polymer structures. [PDF]
, 2017 Two limitations of additive manufacturing methods that arise from layer-based fabrication are slow speed and geometric constraints (which include poor surface quality). Both limitations are overcome in the work reported here, introducing a new volumetric
Browar, Allison EM +7 more
core +2 more sources