Results 71 to 80 of about 1,998,168 (383)
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Mycobacterium tuberculosis is an intracellular pathogen. Within macrophages, M. tuberculosis thrives in a specialized membrane-bound vacuole, the phagosome, whose pH is slightly acidic, and where access to nutrients is limited.
Alexandre Gouzy +15 more
semanticscholar +1 more source
Rachet device transfers loads imposed on latch to support structure before latch springs resist loads, positively locks two pivoted structures on contact, and carries loads in all ...
Ulrich, G. W.
core +1 more source
Recent Advances on Nanocomposite Resists With Design Functionality for Lithographic Microfabrication [PDF]
Eduardo D. Martínez +6 more
openalex +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
OXA-244, an R214G variant of OXA-48, is silently spreading worldwide likely because of difficulties in detection using classical screening media. Here, we characterized two clinical isolates of Escherichia coli and Citrobacter youngae that displayed ...
Camille Gonzalez +8 more
doaj +1 more source
Tantalum alloys resist creep deformation at elevated temperatures [PDF]
Dispersion-strengthened tantalum-base alloys possess high strength and good resistance to creep deformation at elevated temperatures in high vacuum environments.
Buckman, R. W., Jr.
core +1 more source
There have been a number of scientific studies on the question of whether fish feel pain. Some have suggested that some fish indeed do feel pain and that this has significant welfare implications (2003). Others have argued that fish do not have the brain
Wadiwel, Dinesh Joseph
core +3 more sources
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Brain microvascular endothelial cells resist elongation due to curvature and shear stress
The highly specialized endothelial cells in brain capillaries are a key component of the blood-brain barrier, forming a network of tight junctions that almost completely block paracellular transport.
Mao Ye +6 more
semanticscholar +1 more source

