Results 71 to 80 of about 11,899,956 (387)

Why make it if you can take it: review on extracellular cholesterol uptake and its importance in breast and ovarian cancers

Journal of Experimental & Clinical Cancer Research
Cholesterol homeostasis is essential for healthy mammalian cells and dysregulation of cholesterol metabolism contributes to the pathogenesis of various diseases including cancer. Cancer cells are dependent on cholesterol.
Anna Røssberg Lauridsen, Aikaterini Skorda, Nuggi Ingholt Winther, Marie Lund Bay, Tuula Kallunki   +4 more
doaj   +1 more source

Effect of different dietary protein levels and amino acids supplementation patterns on growth performance, carcass characteristics and nitrogen excretion in growing-finishing pigs

Journal of Animal Science and Biotechnology, 2019
Background This study was conducted to determine the effects of different dietary protein levels and amino acids supplementation patterns in low protein diets on the growth performance, carcass characteristics and nitrogen excretion in growing-finishing ...
Yumei Zhao, Gang Tian, Daiwen Chen, Ping Zheng, Jie Yu, Jun He, Xiangbing Mao, Zhiqing Huang, Yuheng Luo, Junqiu Luo, Bing Yu   +10 more
doaj   +1 more source

Integrating whole-genome sequencing within the National Antimicrobial Resistance Surveillance Program in the Philippines

Nature Communications, 2020
Whole-genome sequencing (WGS) can support drug resistance surveillance, but is rare in low- and middle-income countries. Here, the authors integrate WGS within the national antimicrobial resistance surveillance program in the Philippines and conduct a ...
Silvia Argimón, Melissa A. L. Masim, June M. Gayeta, Marietta L. Lagrada, Polle K. V. Macaranas, Victoria Cohen, Marilyn T. Limas, Holly O. Espiritu, Janziel C. Palarca, Jeremiah Chilam, Manuel C. Jamoralin, Alfred S. Villamin, Janice B. Borlasa, Agnettah M. Olorosa, Lara F. T. Hernandez, Karis D. Boehme, Benjamin Jeffrey, Khalil Abudahab, Charmian M. Hufano, Sonia B. Sia, John Stelling, Matthew T. G. Holden, David M. Aanensen, Celia C. Carlos   +23 more
doaj   +1 more source

Silencing of the calcium-dependent protein kinase TaCDPK27 improves wheat resistance to powdery mildew

BMC Plant Biology, 2023
Background Calcium ions (Ca2+), secondary messengers, are crucial for the signal transduction process of the interaction between plants and pathogens. Ca2+ signaling also regulates autophagy.
Jie-yu Yue, Jin-lan Jiao, Wen-wen Wang, Xin-rui Jie, Hua-zhong Wang   +4 more
doaj   +1 more source

Resiting French resistance [PDF]

, 1999
Exceptions, minorities, non-conformities, individual refusals and small group actions, these are words with which historians of the French Resistance learn to live.
Kedward, H R
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

High prevalence of resistance to third-generation cephalosporins detected among clinical isolates from sentinel healthcare facilities in Lagos, Nigeria

Antimicrobial Resistance and Infection Control, 2022
Background Antimicrobial resistance (AMR) in bacterial pathogens is a worldwide concern that demands immediate attention. Most information on AMR originates from high-income countries and little is known about the burden in Africa, particularly Nigeria ...
Emelda E. Chukwu, Oluwatoyin B. Awoderu, Christian A. Enwuru, Ebelechukwu E. Afocha, Rahman G. Lawal, Rahaman A. Ahmed, Ishola Olanrewaju, Chika K. Onwuamah, Rosemary A. Audu, Folasade T. Ogunsola   +9 more
doaj   +1 more source

Mechanisms of antimicrobial resistance in biofilms

npj Antimicrobials and Resistance
Most bacteria in nature exist in aggregated communities known as biofilms, and cells within a biofilm demonstrate major physiological changes compared to their planktonic counterparts. Biofilms are associated with many different types of infections which
Ho Yu Liu, Emma L. Prentice, Mark A. Webber   +2 more
semanticscholar   +1 more source

Metals to combat antimicrobial resistance

Nature Reviews Chemistry, 2023
Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific metal may be essential for survival yet toxic in certain forms and concentrations.
Angelo Frei, Anthony D. Verderosa, Alysha G. Elliott, J. Zuegg, M. Blaskovich   +4 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source