Results 81 to 90 of about 6,277,435 (292)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Bounds for resistance-distance spectral radius

, 2013
Lower and upper bounds as well as Nordhause-Gaddum-type results for the resistance-distance spectral radius are obtained.
Maden, A. Dilek Gungor, Gutman, Ivan, Cevik, A. Sinan   +2 more
openaire   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

The influence of distance between the floats of catamaran hull

Annals of "Dunărea de Jos" University of Galaţi: Fascicle XI Shipbuilding, 2019
This study presents the influence of the distance between the floats of catamaran for ship calm water resistance. As we know, a catamaran is composed by 2 floats, each float having its own wave systems in calm water.
Alin Pohilca, Matei Cosmin Baciu, Liviu Galateanu, Costel Iulian Mocanu   +3 more
doaj   +1 more source

Resistance Distance and Kirchhoff Index of $Q$ -Double Join Graphs

IEEE Access, 2019
Let $Q(G)$ be the graph derived from $G$ by inserting a new vertex into every edge of $G$ and by connecting edges of these new vertices that are on adjacent edges of $G$ , and $Q$ -double join of $G$ , $G_{1}$ and $G_{2}$ denoted by $G^{Q ...
Weizhong Wang, Tingyan Ma, Jia-bao Liu
semanticscholar   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Extremal values on the Kirchhoff index of the line graph of trees

Kuwait Journal of Science
The computation of resistance distance and the Kirchhoff index is a classical problem that has been extensively investigated by numerous mathematicians, physicists, and scientists. Consider a simple connected graph G with vertex set V(G) and edge set E(G)
doaj   +1 more source

Enhancement the Armor Shielding Properties of CF/epoxy Composite by Addition Nanoparticles of Magnetic Iron Oxide

MATEC Web of Conferences, 2017
In the present investigation, we prepared two types of CF composites. The first prepared composite sample was CF/epoxy resin composite and the second was CF/epoxy resin / with a different weight ratio of magnetic iron oxide.
Fouda Hany, Ghith Khalid, Guo Lin
doaj   +1 more source