Results 121 to 130 of about 108,664 (314)

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen   +19 more
wiley   +1 more source

OPTIMAL CONTROL OF PEST RESISTANCE TO TRANSGENIC CROP VARIETIES [PDF]

open access: yes
Transgenic corn varieties entered the market in 1996. These plant varieties carry a gene from the soil bacterium Bacillus thuringiensis kurstaki, Bt, that makes the plant produce a toxin deadly to the pest insect European Corn Borer (ECB) Ostrinia ...
Huffaker, Ray G., Grimsrud, Kristine M.
core   +1 more source

Genomic and functional characterization of the L‑sorbose phosphotransferase system in high-risk Escherichia coli lineages

open access: yesmSystems
Certain Escherichia coli strains belong to international high-risk clonal lineages exhibiting a combination of multidrug resistance, enhanced fitness, and increased virulence, posing major public health challenges. Investigation of characteristics beyond
Lena-Sophie Swiatek   +10 more
doaj   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

open access: yesAdvanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou   +10 more
wiley   +1 more source

Estimating the Benefits of Bt Corn and Cost of Insect Resistance Management Ex Ante [PDF]

open access: yes
This paper estimates farmer benefits for corn rootworm (CRW) active Bt corn and costs of complying with Environmental Protection Agency insect resistance management requirements.
Ostlie, Kenneth   +2 more
core   +1 more source

Glyphosate resistance in annual ryegrass (Lolium rigidum Gaud.) with multiple resistance mechanisms. [PDF]

open access: yes, 2010
Glyphosate (N-(phosphonomethyl)glycine) is a post-emergent, systemic and non-selective herbicide for the control of annual and perennial weeds. This herbicide has very low toxicity to the mammals.
Bostamam, Yazid
core   +1 more source

Utilizing Olive Fly Ecology Towards Sustainable Pest Management [PDF]

open access: yes
The olive fly (Bactrocera oleae, OLF) is a major pest of global significance that occurs in places where olive cultivation thrives. This paper highlights the economic and environmental damage caused by OLF infestations, including reduced olive oil yield ...
Efstratios Sentas   +4 more
core   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu   +5 more
wiley   +1 more source

From Consumer Resistance to Stakeholder Resistance The case of nanotechnology [PDF]

open access: yes
The development of emerging technologies encounters resistance among heterogeneous actors. A good understanding of that resistance phenomenon may help leaders to take decisions reflecting multiple interests.
Caroline Gauthier
core  

Political ecology of environmental crises in Bangladesh [PDF]

open access: yes, 2006
: Bangladesh suffers from a range of crises affecting its human and non-human environments. The issues are widely discussed, with corrective policies proposed and implemented, but the results so far have not been satisfactory.
Sanyal, Nandini
core  

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