Results 61 to 70 of about 1,075,763 (318)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Resistance Versus Aerobic Exercise [PDF]

open access: yesDiabetes Care, 2013
OBJECTIVE In type 1 diabetes, small studies have found that resistance exercise (weight lifting) reduces HbA1c. In the current study, we examined the acute impacts of resistance exercise on glycemia during exercise and in the subsequent 24 h compared with aerobic exercise and no exercise.
Jane E. Yardley   +8 more
openaire   +1 more source

The effects of ageing and exercise on skeletal muscle structure and function [PDF]

open access: yes, 2016
Musculoskeletal ageing is associated with profound morphological and functional changes that increase fall risk and disease incidence and is characterised by age-related reductions in motor unit number and atrophy of muscle fibres, particularly type II ...
Malone, John K.
core  

A Randomized Controlled Trial of Short-term Toe Resistance Training to Improve Toe Pinch Force in Patients with Type 2 Diabetes [PDF]

open access: yes, 2018
Resistance training is effective against type 2 diabetes (T2DM), but the effect of resistance training on toe pinch force (TPF) is unknown. Here we investigated the effect of short-term toe resistance training on TPF in patients with T2DM, in a ...
Kataoka, Hiroaki   +3 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Tachycardia During Resistance Exercise

open access: yesJournal of Strength and Conditioning Research, 2001
A male weight-trained (WT) subject (A; age = 21 years, height = 193.6 cm, body weight = 113.4 kg, parallel barbell squat 10 repetition maximum [RM] = 183.7 kg) and a group of 18 similarly trained men (WT; X +/- SD; age = 24.7 +/- 3.0 years, height = 180.2 +/- 4.3 cm, body weight = 86.9 +/- 10.7 kg, 10 RM = 127.9 +/- 28.6 kg) were monitored during a ...
A C, Fry, M J, Parks
openaire   +3 more sources

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Effect of exercise order of resistance exercise on serum cellular damage enzymes in untrained men [PDF]

open access: yesفیزیولوژی ورزش و فعالیت بدنی, 2013
Background and Objective: The exercise order refers to the sequence of resistance exercises in a training session. The objective of this study was to investigate the influence of different resistance exercise execution orders on the Creatine kinase (CK ...
کمال عزیز بیگی   +2 more
doaj   +1 more source

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