Results 211 to 220 of about 2,975,301 (351)

Overcoming the sorafenib resistance mechanism in FLT3-mutated acute myeloid leukemia: molecular basis and new targets. [PDF]

Front Oncol
Peng H, Li M, Peng YY, Li XL, Yang J, Sun QG, Song K.   +6 more
europepmc   +1 more source

Supplementary materials-Anti-Insulin Resistance Mechanism of Action of Glycyrrhizic Acid An in Vitro Investigation Based on in Silico Prediction

, 2019
Haoru Zhu
openalex   +1 more source

DDIS-11. MOLECULAR MECHANISMS OF DIANHYDROGALACTITOL (VAL-083) IN OVERCOMING CHEMO-RESISTANCE IN GLIOBLASTOMA [PDF]

, 2016
Beibei Zhai, Anna Golebiewska, Anne Steinø, Jeffrey Bacha, Dennis Brown, Simone P. Niclou, Mads Daugaard   +6 more
openalex   +1 more source

Emerging strategies to target metastasis and therapy resistance in melanoma

Molecular Oncology, EarlyView.
Emerging studies propose new approaches to interfere with melanoma progression. In recognition of melanoma awareness month, at Molecular Oncology, we highlight recently published research articles, focusing on novel therapeutic targets driving metastatic spread and outlining different strategies to overcome resistance to BRAF inhibitors and anti‐PD‐1 ...
Amel Aziba
wiley   +1 more source

Genome-wide CRISPR Screening Reveals a PKA-Driven Resistance Mechanism to Metformin for Oral Cancer Prevention That Can Be Exploited by Combination with NSAIDs. [PDF]

Cancer Prev Res (Phila)
Hoang TS, Faraji F, Mendez-Molina AN, Adame-Garcia SR, Sato K, Ishikawa T, Vo PTT, Ramirez SI, Anguiano Quiroz PY, Guo T, Fan K, Wu X, Molinolo AA, Cohen EEW, Mali P, Lippman SM, Gutkind JS.   +16 more
europepmc   +1 more source

Correction: Hedgehog Fights Back: Mechanisms of Acquired Resistance against Smoothened Antagonists [PDF]

, 2011
C Metcalfe, F De Sauvage
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A metabolite-based resistance mechanism against malaria. [PDF]

Science
Figueiredo A, Rastogi ST, Ramos S, Nogueira F, De Villiers K, de Sousa AGG, Votborg-Novél L, von Wedel C, Tober-Lau P, Jentho E, Pagnotta S, Mesquita M, Cardoso S, Bortolussi G, Muro AF, Tranfield EM, Thibaud J, Duarte D, Sousa AL, Sousa AL, Pinto SN, Kitoko J, Mombo-Ngoma G, Mischlinger J, Junttila S, Alenquer M, Amorim MJ, Vasavda C, Bosma PJ, Violante S, Drotleff B, Paixão T, Portugal S, Kurth F, Elo LL, Paul BD, Martins R, Soares MP.   +37 more
europepmc   +1 more source

Rox, a Rifamycin Resistance Enzyme with an Unprecedented Mechanism of Action [PDF]

, 2018
Kalinka Koteva, Georgina Cox, Jayne Kelso, Matthew D. Surette, Haley L. Zubyk, Linda Ejim, P.J. Stogios, Alexei Savchenko, Dan Sørensen, Gerard D. Wright   +9 more
openalex   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source